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Automated Interpretation of Blood Culture Gram Stains by Use of a Deep Convolutional Neural Network.

Publication: Journal Article

Smith, Kenneth P, Anthony D Kang, and James E Kirby. 2018. “Automated Interpretation of Blood Culture Gram Stains by Use of a Deep Convolutional Neural Network.”. Journal of Clinical Microbiology 56 (3).

Improved Accuracy of Cefepime Susceptibility Testing for Extended-Spectrum-Beta-Lactamase-Producing Enterobacteriaceae with an On-Demand Digital Dispensing Method.

Publication: Journal Article

Smith, Kenneth P, Thea Brennan-Krohn, Susan Weir, and James E Kirby. 2017. “Improved Accuracy of Cefepime Susceptibility Testing for Extended-Spectrum-Beta-Lactamase-Producing Enterobacteriaceae With an On-Demand Digital Dispensing Method.”. Journal of Clinical Microbiology 55 (2): 470-78.

High Throughput, Real-time, Dual-readout Testing of Intracellular Antimicrobial Activity and Eukaryotic Cell Cytotoxicity.

Publication: Journal Article

Chiaraviglio, Lucius, Yoon-Suk Kang, and James E Kirby. 2016. “High Throughput, Real-Time, Dual-Readout Testing of Intracellular Antimicrobial Activity and Eukaryotic Cell Cytotoxicity.”. Journal of Visualized Experiments : JoVE, no. 117.

Susceptibility of Multidrug-Resistant Gram-Negative Urine Isolates to Oral Antibiotics.

Publication: Journal Article

Hirsch, Elizabeth B, Paola C Zucchi, Alice Chen, Brian R Raux, James E Kirby, Christopher McCoy, and George M Eliopoulos. 2016. “Susceptibility of Multidrug-Resistant Gram-Negative Urine Isolates to Oral Antibiotics.”. Antimicrobial Agents and Chemotherapy 60 (5): 3138-40.

Heidi Alhannat

Person: Undergraduate

Heidi joined us in the summer of 2024. A Harvard College sophomore, Heidi is growing vast quantities of Streptomyces with much aeration and fanfare to induce them to produce copious quantities of antimicrobials amongst other biological feats in the laboratory! Outside of the laboratory Heidi loves...

Cryo-EM structure of the Pseudomonas aeruginosa MexY multidrug efflux pump.

Publication: Journal Article

Gregor, William D, Rakesh Maharjan, Zhemin Zhang, Lucius Chiaraviglio, Nithya Sastry, Meng Cui, James E Kirby, and Edward W Yu. 2025. “Cryo-EM Structure of the Pseudomonas Aeruginosa MexY Multidrug Efflux Pump.”. MBio 16 (4): e0382624.

Exploration of the Fusidic Acid Structure Activity Space for Antibiotic Activity.

Publication: Journal Article

Kang, Yoon-Suk, Simone C Silva, Kenneth Smith, Krissty Sumida, Yuhan Wang, Lucius Chiaraviglio, Ramachandra Reddy Donthiri, Alhanouf Z Aljahdali, James E Kirby, and George A O’Doherty. 2025. “Exploration of the Fusidic Acid Structure Activity Space for Antibiotic Activity.”. Molecules (Basel, Switzerland) 30 (3).

Novel strain of multidrug non-susceptible Neisseria gonorrhoeae in the USA.

Publication: Journal Article

Reimche, Jennifer L, Cau D Pham, Sandeep J Joseph, Shelby Hutton, John C Cartee, Yuheng Ruan, Mandy Breaux, et al. 2024. “Novel Strain of Multidrug Non-Susceptible Neisseria Gonorrhoeae in the USA.”. The Lancet. Infectious Diseases 24 (3): e149-e151.

A Versatile Nanoluciferase Reporter Reveals Structural Properties Associated with a Highly Efficient, N-Terminal Legionella pneumophila Type IV Secretion Translocation Signal.

Publication: Journal Article

Kang, Yoon-Suk, and James E Kirby. 2023. “A Versatile Nanoluciferase Reporter Reveals Structural Properties Associated With a Highly Efficient, N-Terminal Legionella Pneumophila Type IV Secretion Translocation Signal.”. Microbiology Spectrum 11 (2): e0233822.

Outcomes associated with empiric cefepime for bloodstream infections caused by ceftriaxone-resistant, cefepime-susceptible Escherichia coli and Klebsiella pneumoniae.

Publication: Journal Article

Frescas, Brian E, Christopher M McCoy, James Kirby, Robert Bowden, and Nicholas J Mercuro. 2023. “Outcomes Associated With Empiric Cefepime for Bloodstream Infections Caused by Ceftriaxone-Resistant, Cefepime-Susceptible Escherichia Coli and Klebsiella Pneumoniae.”. International Journal of Antimicrobial Agents 61 (5): 106762.