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Research

My research program is rooted in clinically grounded, outcomes-driven investigation aimed at improving care for patients with pelvic floor disorders. Across projects, I focus on questions that arise directly from clinical practice, studying how surgical technique, perioperative care, and health...

BIDMC Glycomics Core Launches SUGA for Rapid N-Glycan Profiling

Many biologically critical proteins such as viral surface proteins (including SARS-CoV-2 spike), antibodies, and cell-surface receptors are heavily glycosylated, and these sugars can profoundly influence protein function, stability, immune recognition, and drug response. A new Journal of Proteome...

Fine-Tuning Lipid Metabolism by Targeting Mitochondria-Associated Acetyl-CoA-Carboxylase 2 in BRAFV600E Papillary Thyroid Carcinoma.

Valvo, Veronica, Asumi Iesato, Taylor R Kavanagh, Carmen Priolo, Zsuzsanna Zsengeller, Alfredo Pontecorvi, Isaac E Stillman, Suzanne D Burke, Xiaowen Liu, and Carmelo Nucera. 2021. “Fine-Tuning Lipid Metabolism by Targeting Mitochondria-Associated Acetyl-CoA-Carboxylase 2 in BRAFV600E Papillary Thyroid Carcinoma.”. Thyroid : Official Journal of the American Thyroid Association 31 (9): 1335-58.

Vemurafenib-resistance via de novo RBM genes mutations and chromosome 5 aberrations is overcome by combined therapy with palbociclib in thyroid carcinoma with BRAFV600E.

Antonello, Zeus A, Nancy Hsu, Manoj Bhasin, Giovanni Roti, Mukta Joshi, Paul Van Hummelen, Emily Ye, et al. 2017. “Vemurafenib-Resistance via de Novo RBM Genes Mutations and Chromosome 5 Aberrations Is Overcome by Combined Therapy With Palbociclib in Thyroid Carcinoma With BRAFV600E.”. Oncotarget 8 (49): 84743-60.