From genome-wide association studies to etiology: probing autoimmunity genes by RNAi
Kissler, Stephan. 2011. “From Genome-Wide Association Studies to Etiology: Probing Autoimmunity Genes by RNAi”. Trends Mol Med 17 (11): 634-40.
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In vivo RNA interference demonstrates a role for Nramp1 in modifying susceptibility to type 1 diabetes
Kissler, Stephan, Patrick Stern, Kazue Takahashi, Kara Hunter, Laurence Peterson, and Linda Wicker. 2006. “In Vivo RNA Interference Demonstrates a Role for Nramp1 in Modifying Susceptibility to Type 1 Diabetes”. Nat Genet 38 (4): 479-83.
T cell costimulation through CD28 depends on induction of the Bcl-xgamma isoform: analysis of Bcl-xgamma-deficient mice
Ye, Qunrui, Barry Press, Stephan Kissler, Xiao-Feng Yang, Linrong Lu, Craig Bassing, Barry Sleckman, et al. 2002. “T Cell Costimulation through CD28 Depends on Induction of the Bcl-Xgamma Isoform: Analysis of Bcl-Xgamma-Deficient Mice”. J Exp Med 196 (1): 87-95.
Regulation of thymocyte trafficking by tagap, a GAP-domain protein linked to human autoimmunity
Duke-Cohan, JS, Ishikawa, Yoshizawa, YI Choi, Lee, Acuto, Kissler*, and EL Reinherz*. 2018. “Regulation of Thymocyte Trafficking by Tagap, a GAP-Domain Protein Linked to Human Autoimmunity”. Science Signaling 11 (534): eaan8799.
The autoimmunity-associated gene RGS1 affects the frequency of T follicular helper cells
Caballero-Franco, Celia, and Stephan Kissler. 2016. “The Autoimmunity-Associated Gene RGS1 Affects the Frequency of T Follicular Helper Cells”. Genes Immun 17 (4): 228-38.
PTPN22 silencing in the NOD model indicates the type 1 diabetes-associated allele is not a loss-of-function variant
Zheng, Peilin, and Stephan Kissler. 2013. “PTPN22 Silencing in the NOD Model Indicates the Type 1 Diabetes-Associated Allele Is Not a Loss-of-Function Variant”. Diabetes 62 (3): 896-904.
The soluble CTLA-4 splice variant protects from type 1 diabetes and potentiates regulatory T-cell function
Gerold, Kay, Peilin Zheng, Daniel Rainbow, Alma Zernecke, Linda Wicker, and Stephan Kissler. 2011. “The Soluble CTLA-4 Splice Variant Protects from Type 1 Diabetes and Potentiates Regulatory T-Cell Function”. Diabetes 60 (7): 1955-63.
Rnai as an experimental and therapeutic tool to study and regulate physiological and disease processes
Dillon, Christopher, Peter Sandy, Alessio Nencioni, Stephan Kissler, Douglas Rubinson, and Luk Van Parijs. 2005. “Rnai As an Experimental and Therapeutic Tool to Study and Regulate Physiological and Disease Processes”. Annu Rev Physiol 67: 147-73.
RNA interference for the identification of disease-associated genes
Nencioni, Alessio, Peter Sandy, Christopher Dillon, Stephan Kissler, Peter Blume-Jensen, and Luk Van Parijs. 2004. “RNA Interference for the Identification of Disease-Associated Genes”. Curr Opin Mol Ther 6 (2): 136-40.
Cross-reactivity and T-cell receptor antagonism of myelin basic protein-reactive T cells is modulated by the activation state of the antigen presenting cell
Kissler, Stephan, Stephen Anderton, and David Wraith. 2002. “Cross-Reactivity and T-Cell Receptor Antagonism of Myelin Basic Protein-Reactive T Cells Is Modulated by the Activation State of the Antigen Presenting Cell”. J Autoimmun 19 (4): 183-93.