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The Benson Lab uses metabolomic and proteomic plasma profiling techniques to make observations in humans that can then be brought back to the bench for biomarker and pathway discovery in cardiometabolic disease.

Energy Balance Metabolic Core at BIDMC, measurement of energy intake, nutritional status, and energy expenditure in experimental mice

Histology Core at BIDMC, provide services in paraffin histology for cells and tissues, Embedding, Sectioning, Routine staining

Electron Microscopy Core at BIDMC, Tissue processing for Transmission Electron Microscopy, Sectioning for Transmission Electron Microscopy, Ultrastructural analysis and image processing

At the Center for Drug Discovery and Translational Research, BIDMC, Harvard Medical School, Sun Lab offers a platform and expertise in medicinal chemistry to facilitate the translation of research from bench to bedside.
Our laboratory has studied the optimal integration of molecular simulations into the generation of bioactive molecules. In collaboration with investigators at Harvard Medical School, we have applied this research methodology to discover novel immune modulators for the treatment of autoimmune diseases (e.g., Inflammatory Bowel Diseases, Diabetes, etc) and cancers (e.g., Breast cancer). Currently, our interest focuses on Aryl Hydrocarbon Receptor (AHR) modulators, Orai channel blockers, and threonine/serine kinases.

Chemical Biology, Biochemistry, Beth Israel

Immunology Technologies Core at BIDMC, flow cytometric, histotechnology and spatial-omics data generation services

The Functional Genomics and Bioinformatics Core (FunGen Core) at BIDMC provides investigators with end-to-end support for transcriptomic and multiomic studies—from experimental design to data interpretation.