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Pathophysiology of Dystonia

Dystonia is a movement disorder of yet unknown causes and pathophysiology. It is characterized by sustained or intermittent muscle contractions causing abnormal, often repetitive, movements, postures, or both. Focal dystonias are the most common forms of dystonia and can affect different muscle...

Eye Witness 36 - June 2018

Inside issue #36: Artificial Intelligence in Ophthalmology Meet our New Glaucoma Specialists Review Websites Offer Insight into Patient Experience Dr. Miller Honored with Retina Research Awards Dr. D'Amore Elected to Prestigious Academy Download the full issue or read highlights below. Artificial...

Letter From the Chair

The Harvard Combined Training Program in Otolaryngology–Head and Neck Surgery offers extensive exposure to all clinical aspects of the specialty across several different venues with the ability to interact with a large number of faculty. This includes novel simulation exercises in our state-of-the...

Asparagine-Linked Glycan Array

Publication: Gao C, Hanes MS, Byrd-Leotis LA, Wei M, Jia N, Kardish RJ, McKitrick TR, Steinhauer DA, Cummings RD. Unique Binding Specificities of Proteins toward Isomeric Asparagine-Linked Glycans. Cell Chem Biol. 2019 Apr 18;26(4):535-547.e4. doi: 10.1016/j.chembiol.2019.01.002. Epub 2019 Feb 7...

Lab members

Current members Stephan Kissler, PhD – Principal Investigator Tara Macdonald, PhD - Postdoctoral fellow Kevin Bode, PhD - Postdoctoral fellow Celia Vived, PhD - Postdoctoral fellow Gabriela Ramirez, PhD - Postdoctoral fellow Bryhan Mendez - Research Assistant Past members Postdoctoral Fellows Badr...

Research

Our goal is to develop small molecules that modulate cardiometabolic disease-associated genes. To achieve this objective, our lab focuses on the following activities: genetic discovery in human cohorts, genome editing in zebrafish and human cell lines, mass spectrometry-based metabolite profiling...

Current Funding

R01 CA228029 (PI: Perelman)Spectro-Holographic Instrument for Dynamic Sensing of Cancer ProgressionProject Dates: 2018 - 2023Budget: $3.5M R01 CA205431 (PI: Perelman)Isolation and Assessment of Blood-Circulating Cancer Exosomes with LSS and SERS Lab on a Chip Optical Spectroscopic InstrumentProject...

Test

The Center for Advanced Biomedical Imaging and Photonics studies the interaction of light with biological tissue on the microscopic and macroscopic scale. Scientists at the Center work at the interface of biophotonics, bioengineering and cancer biology, with a particular emphasis on: · scattering of...