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Alcohol and Monocyte and Neutrophil Signaling

Macrophages (MØ), Kupffer cells (KC), and neutrophils mediate inflammation and play an important role in the pathogenesis of alcohol-associated liver disease (ALD). Previous studies have demonstrated the damaging effects of pro-inflammatory macrophages on alcoholic liver inflammation and high...

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Providing Expertise in Design and Implementation of Pre-clinical Trials in Mouse Models This facility will work as a resource specializing in preclinical testing in GEMs (genetically engineered mouse models) for investigators with preliminary evidence that an agent or a combination of drugs may...

HPA Sigma

HPA (Helix pomatia agglutinin) Fluorescein Lectins Catalog Number: Biotinylated Lectins Catalog Number: L6512 Lot Number CFG Data Files QAQC Data Files Image Links SLBP70880 CFG QAQC

Clinical Alcoholic Hepatitis

Alcoholic Hepatitis Clinical and Translational Network Late Phase Clinical Trials and Observational Studies Alcoholic liver disease (ALD) is a major cause of liver-related morbidity and mortality in the US. Alcoholic hepatitis (AH) is a life-threatening form of ALD. Severe AH is associated with a...