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From astronomy to cell biology, the manner in which light propagates in turbid media has been of central importance for many decades. The theory of radiative transfer is widely used to treat this problem by considering the transport of light energy through a random medium and neglecting the wave...

The purpose of this program is to develop optical systems that can perform rapid optical scanning and multispectral imaging of the entire epithelial surface of various organs in the in the human digestive system and present a diagnosis in near real time. This approach should be vastly superior to...

Lev T. Perelman is Professor at Harvard and Director of the Center for Advanced Biomedical Imaging and Photonics at Beth Israel Deaconess Medical Center. Prior to that he was Principal Scientist and Group Head at MIT. Perelman’s research interests are primarily focused on application of optics to...

On the Cover Small • November 26, 2018 In article Picoanalysis of Drugs in Biofluids with Quantitative Label‐Free Surface‐Enhanced Raman Spectroscopy, Lev T. Perelman and co‐workers report a quantitative label‐free surface‐enhanced Raman spectroscopy (SERS) method for identifying and quantifying...

Propagation of Light in Turbid Media From astronomy to cell biology, the manner in which light propagates in turbid media has been of central importance for many decades. The theory of radiative transfer is widely used to treat this problem by considering the transport of light energy through a...

Despite the fact that cancer is a disease caused by genetic abnormalities, the most widely accepted means of diagnosing and characterizing cancer cells is with H&E stained microscopic imaging. The identifying features of cancer include abnormally large and crowded cell nuclei with altered cellular...

The enormous increase of Raman signal in the vicinity of metal nanoparticles allows surface-enhanced Raman spectroscopy (SERS) to be employed for label-free detection of substances at extremely low concentrations. However, the ultimate potential of label-free SERS to identify pharmaceutical...

We gained new insight into the potential for some types of extracellular RNA called microRNA (miRNA) to influence cancer progression ( Cancer Cell 2014 ). The research suggests that cancer cell exosomes, vesicles that are secreted by cells and present in many biological fluids, and the associated...