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We have successfully identified multiple novel genetic associations between AD and common and rare variants in endolysosomal genes ( PLD3, RAB10, GRN12, TMEM106B, CPAMD8, MS4A4A). Recently, we performed a systematic, comprehensive evaluation of the contribution of coding variants in each...

This project aims to establish a repository of biosamples in patients with varying neurologic disorders. The proposed biorepository aims to collect a variety of high-quality biosamples and relate them to clinical information to support the accelerated identification of disease biomarkers for earlier...

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Employment Opportunities The Benitez Laboratory is looking for talented and motivated investigators interested in translational neuroscience research at both the basic and clinical levels. We may have vacancies for research assistants, postdoctoral associates, and visiting fellows/scholars at any...

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One of the research interests in our lab is focused on the deep-molecular characterization of a clinically well-defined cohort of patients anchored in genomic data. Alzheimer’s (AD) and Parkinson’s disease (PD) are heterogeneous disorders with identifiable clinical-pathological subtypes based on...

Nuclei Isolation from human cortical tissue for enrichment of endothelial and microglial cells Click Here GitHub for scripts, data, and protocols