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Propagation of Light in Turbid Media From astronomy to cell biology, the manner in which light propagates in turbid media has been of central importance for many decades. The theory of radiative transfer is widely used to treat this problem by considering the transport of light energy through a...

Despite the fact that cancer is a disease caused by genetic abnormalities, the most widely accepted means of diagnosing and characterizing cancer cells is with H&E stained microscopic imaging. The identifying features of cancer include abnormally large and crowded cell nuclei with altered cellular...

From astronomy to cell biology, the manner in which light propagates in turbid media has been of central importance for many decades. The theory of radiative transfer is widely used to treat this problem by considering the transport of light energy through a random medium and neglecting the wave...

The purpose of this program is to develop optical systems that can perform rapid optical scanning and multispectral imaging of the entire epithelial surface of various organs in the in the human digestive system and present a diagnosis in near real time. This approach should be vastly superior to...

Lev T. Perelman is Professor at Harvard and Director of the Center for Advanced Biomedical Imaging and Photonics at Beth Israel Deaconess Medical Center. Prior to that he was Principal Scientist and Group Head at MIT. Perelman’s research interests are primarily focused on application of optics to...

On the Cover Small • November 26, 2018 In article Picoanalysis of Drugs in Biofluids with Quantitative Label‐Free Surface‐Enhanced Raman Spectroscopy, Lev T. Perelman and co‐workers report a quantitative label‐free surface‐enhanced Raman spectroscopy (SERS) method for identifying and quantifying...

Center for Advanced Biomedical Imaging and Photonics studies the interaction of light with biological tissue on the microscopic and macroscopic scale. Scientists at the Center work at the interface of biophotonics, bioengineering and cancer biology, with a particular emphasis on: scattering of...

Perelman LT, Modell MD, Vitkin EI and Hanlon EB. Chapter 9. Light Scattering Spectroscopy: From Elastic to Inelastic. In: Tuchin V, editor. Coherent-Domain Optical Methods for Biomedical Diagnostics, Environmental and Material Science. Bristol and Philadelphia: Institute of Physics Publishing; 2004...

R01 CA228029 (PI: Perelman)Spectro-Holographic Instrument for Dynamic Sensing of Cancer ProgressionProject Dates: 2018 - 2023Budget: $3.5M R01 CA205431 (PI: Perelman)Isolation and Assessment of Blood-Circulating Cancer Exosomes with LSS and SERS Lab on a Chip Optical Spectroscopic InstrumentProject...