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31 results found

IL-17 silencing does not protect nonobese diabetic mice from autoimmune diabetes

Publication: Journal Article

Joseph, Julie, Stefan Bittner, Fabian Kaiser, Heinz Wiendl, and Stephan Kissler. 2012. “IL-17 Silencing Does Not Protect Nonobese Diabetic Mice from Autoimmune Diabetes”. J Immunol 188 (1): 216-21.

STIM1-independent T cell development and effector function in vivo

Publication: Journal Article

Beyersdorf, Niklas, Attila Braun, Timo Vögtle, David Varga-Szabo, Ronmy Rivera Galdos, Stephan Kissler, Thomas Kerkau, and Bernhard Nieswandt. 2009. “STIM1-Independent T Cell Development and Effector Function in Vivo”. J Immunol 182 (6): 3390-7.

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The focus of our research is type 1 diabetes, an autoimmune disease that causes the loss of insulin-producing cells in the pancreas. Type 1 diabetes cannot be prevented or cured. Our goal is to change this by exploring new strategies to shut-down the autoimmune attack on the pancreas and to protect...

The autoimmunity-associated gene RGS1 affects the frequency of T follicular helper cells

Publication: Journal Article

Caballero-Franco, Celia, and Stephan Kissler. 2016. “The Autoimmunity-Associated Gene RGS1 Affects the Frequency of T Follicular Helper Cells”. Genes Immun 17 (4): 228-38.

PTPN22 silencing in the NOD model indicates the type 1 diabetes-associated allele is not a loss-of-function variant

Publication: Journal Article

Zheng, Peilin, and Stephan Kissler. 2013. “PTPN22 Silencing in the NOD Model Indicates the Type 1 Diabetes-Associated Allele Is Not a Loss-of-Function Variant”. Diabetes 62 (3): 896-904.

The soluble CTLA-4 splice variant protects from type 1 diabetes and potentiates regulatory T-cell function

Publication: Journal Article

Gerold, Kay, Peilin Zheng, Daniel Rainbow, Alma Zernecke, Linda Wicker, and Stephan Kissler. 2011. “The Soluble CTLA-4 Splice Variant Protects from Type 1 Diabetes and Potentiates Regulatory T-Cell Function”. Diabetes 60 (7): 1955-63.

Rnai as an experimental and therapeutic tool to study and regulate physiological and disease processes

Publication: Journal Article

Dillon, Christopher, Peter Sandy, Alessio Nencioni, Stephan Kissler, Douglas Rubinson, and Luk Van Parijs. 2005. “Rnai As an Experimental and Therapeutic Tool to Study and Regulate Physiological and Disease Processes”. Annu Rev Physiol 67: 147-73.

RNA interference for the identification of disease-associated genes

Publication: Journal Article

Nencioni, Alessio, Peter Sandy, Christopher Dillon, Stephan Kissler, Peter Blume-Jensen, and Luk Van Parijs. 2004. “RNA Interference for the Identification of Disease-Associated Genes”. Curr Opin Mol Ther 6 (2): 136-40.

Cross-reactivity and T-cell receptor antagonism of myelin basic protein-reactive T cells is modulated by the activation state of the antigen presenting cell

Publication: Journal Article

Kissler, Stephan, Stephen Anderton, and David Wraith. 2002. “Cross-Reactivity and T-Cell Receptor Antagonism of Myelin Basic Protein-Reactive T Cells Is Modulated by the Activation State of the Antigen Presenting Cell”. J Autoimmun 19 (4): 183-93.

Therapeutic potential of TCR antagonists is determined by their ability to modulate a diverse repertoire of autoreactive T cells

Publication: Journal Article

Anderton, Kissler, Lamont, and Wraith. 1999. “Therapeutic Potential of TCR Antagonists Is Determined by Their Ability to Modulate a Diverse Repertoire of Autoreactive T Cells”. Eur J Immunol 29 (6): 1850-7.