From genome-wide association studies to etiology: probing autoimmunity genes by RNAi
Kissler, Stephan. 2011. “From Genome-Wide Association Studies to Etiology: Probing Autoimmunity Genes by RNAi”. Trends Mol Med 17 (11): 634-40.
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In vivo RNA interference demonstrates a role for Nramp1 in modifying susceptibility to type 1 diabetes
Kissler, Stephan, Patrick Stern, Kazue Takahashi, Kara Hunter, Laurence Peterson, and Linda Wicker. 2006. “In Vivo RNA Interference Demonstrates a Role for Nramp1 in Modifying Susceptibility to Type 1 Diabetes”. Nat Genet 38 (4): 479-83.
T cell costimulation through CD28 depends on induction of the Bcl-xgamma isoform: analysis of Bcl-xgamma-deficient mice
Ye, Qunrui, Barry Press, Stephan Kissler, Xiao-Feng Yang, Linrong Lu, Craig Bassing, Barry Sleckman, et al. 2002. “T Cell Costimulation through CD28 Depends on Induction of the Bcl-Xgamma Isoform: Analysis of Bcl-Xgamma-Deficient Mice”. J Exp Med 196 (1): 87-95.
Regulation of thymocyte trafficking by tagap, a GAP-domain protein linked to human autoimmunity
Duke-Cohan, JS, Ishikawa, Yoshizawa, YI Choi, Lee, Acuto, Kissler*, and EL Reinherz*. 2018. “Regulation of Thymocyte Trafficking by Tagap, a GAP-Domain Protein Linked to Human Autoimmunity”. Science Signaling 11 (534): eaan8799.
CD5 controls gut immunity by shaping the cytokine profile of intestinal T cells
Schuster, Cornelia, Badr Kiaf, Teri Hatzihristidis, Anna Ruckdeschel, Janice Nieves-Bonilla, Yuki Ishikawa, Bin Zhao, Peilin Zheng, Paul Love, and Stephan Kissler. In Press. “CD5 Controls Gut Immunity by Shaping the Cytokine Profile of Intestinal T Cells”. Frontiers in Immunology, In Press.
IMMUN301QC - Autoimmunity - Neoantigens
This two hour class is part of the IMMUN301QC course on Autoimmunity organized by Francisco Quintana . The class discusses the generation of neoantigens in cells that are targeted by autoimmunity. It includes a discussion of tw0 significant primary publications on this topic.
Kissler Lab
Increased β-Cell Proliferation Before Immune Cell Invasion Prevents Progression of Type 1 Diabetes
E, Dirice, Kahraman S, De Jesus D, . , Kissler S, and Kulkarni RN. 2019. “Increased β-Cell Proliferation Before Immune Cell Invasion Prevents Progression of Type 1 Diabetes”. Nat Metab 1 (5): 509-18.
Exploring the genetic basis of disease using RNA interference
Kissler, Stephan, and Luk Van Parijs. 2004. “Exploring the Genetic Basis of Disease Using RNA Interference”. Expert Rev Mol Diagn 4 (5): 645-51.
Thymic selection can compensate for mutations affecting T cell activation and generate a normal T cell repertoire in mutant mice
Kissler, Stephan, Linrong Lu, and Harvey Cantor. 2004. “Thymic Selection Can Compensate for Mutations Affecting T Cell Activation and Generate a Normal T Cell Repertoire in Mutant Mice”. Proc Natl Acad Sci U S A 101 (1): 210-4.