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33 results found

Regulation of Glucose Uptake and Enteroendocrine Function by the Intestinal Epithelial Insulin Receptor

Publication: Journal Article

Ussar, Siegfried, Max-Felix Haering, Shiho Fujisaka, Dominik Lutter, Kevin Lee, Ning Li, Georg Gerber, Lynn Bry, and C. Ronald Kahn. 2017. “Regulation of Glucose Uptake and Enteroendocrine Function by the Intestinal Epithelial Insulin Receptor”. Diabetes.

Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis

Publication: Journal Article

O’Neill, Brian, Kevin Lee, Katherine Klaus, Samir Softic, Megan Krumpoch, Joachim Fentz, Kristin Stanford, et al. 2016. “Insulin and IGF-1 Receptors Regulate FoxO-Mediated Signaling in Muscle Proteostasis”. J Clin Invest 126 (9): 3433-46.

Insulin resistance in brain alters dopamine turnover and causes behavioral disorders

Publication: Journal Article

Kleinridders, Andre, Weikang Cai, Laura Cappellucci, Armen Ghazarian, William Collins, Sara Vienberg, Emmanuel Pothos, and Ronald Kahn. 2015. “Insulin Resistance in Brain Alters Dopamine Turnover and Causes Behavioral Disorders”. Proc Natl Acad Sci U S A 112 (11): 3463-8.

Insulin signaling and environment

Page

Microbiome as an environmental modifier of insulin resistance Mitochondrial metabolism, sirtuins, metabolism, aging and stress resistance Fructose and high fat diet as modifiers of metabolic syndrome Modeling insulin resistance and diabetes with human iPS cells Role of miRNAs in insulin action and...

ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes

Publication: Journal Article

Ussar, Siegfried, Kevin Lee, Simon Dankel, Jeremie Boucher, Max-Felix Haering, Andre Kleinridders, Thomas Thomou, et al. 2014. “ASC-1, PAT2, and P2RX5 Are Cell Surface Markers for White, Beige, and Brown Adipocytes”. Sci Transl Med 6 (247): 247ra103.

Adipocyte Dynamics and Reversible Metabolic Syndrome in Mice with an Inducible Adipocyte-Specific Deletion of the Insulin Receptor

Publication: Journal Article

Sakaguchi, Masaji, Shiho Fujisaka, Weikang Cai, Jonathon Winnay, Masahiro Konishi, Brian O’Neill, Mengyao Li, et al. 2017. “Adipocyte Dynamics and Reversible Metabolic Syndrome in Mice With an Inducible Adipocyte-Specific Deletion of the Insulin Receptor”. Cell Metab 25 (2): 448-62.

Antibiotic effects on gut microbiota and metabolism are host dependent

Publication: Journal Article

Fujisaka, Shiho, Siegfried Ussar, Clary Clish, Suzanne Devkota, Jonathan Dreyfuss, Masaji Sakaguchi, Marion Soto, et al. 2016. “Antibiotic Effects on Gut Microbiota and Metabolism Are Host Dependent”. J Clin Invest 126 (12): 4430-43.

Role of microRNA processing in adipose tissue in stress defense and longevity

Publication: Journal Article

Mori, Marcelo, Prashant Raghavan, Thomas Thomou, Jeremie Boucher, Stacey Robida-Stubbs, Yazmin Macotela, Steven Russell, James Kirkland, Keith Blackwell, and Ronald Kahn. 2012. “Role of MicroRNA Processing in Adipose Tissue in Stress Defense and Longevity”. Cell Metab 16 (3): 336-47.

Leptin regulation of Hsp60 impacts hypothalamic insulin signaling

Publication: Journal Article

Kleinridders, Andre, Hans Lauritzen, Siegfried Ussar, Jane Christensen, Marcelo Mori, Peter Bross, and Ronald Kahn. 2013. “Leptin Regulation of Hsp60 Impacts Hypothalamic Insulin Signaling”. J Clin Invest 123 (11): 4667-80.

Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation

Publication: Journal Article

Jing, Enxuan, Brian O’Neill, Matthew Rardin, Andre Kleinridders, Olga Ilkeyeva, Siegfried Ussar, James Bain, et al. 2013. “Sirt3 Regulates Metabolic Flexibility of Skeletal Muscle through Reversible Enzymatic Deacetylation”. Diabetes 62 (10): 3404-17.