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16 results found

Early Increased Urinary IL-2 and IL-10 Levels Were Associated With Development of Chronic UTI in a Murine Model.

Publication: Journal Article

Zhu, Kejia, Warren G Hill, Fangyong Li, Benkang Shi, and Toby C Chai. 2020. “Early Increased Urinary IL-2 and IL-10 Levels Were Associated With Development of Chronic UTI in a Murine Model.”. Urology 141: 188.e1-188.e6.

Cis P-tau underlies vascular contribution to cognitive impairment and dementia and can be effectively targeted by immunotherapy in mice.

Publication: Journal Article

Qiu, Chenxi, Onder Albayram, Asami Kondo, Bin Wang, Nami Kim, Ken Arai, Cheng-Yu Tsai, et al. 2021. “Cis P-Tau Underlies Vascular Contribution to Cognitive Impairment and Dementia and Can Be Effectively Targeted by Immunotherapy in Mice.”. Science Translational Medicine 13 (596).

Reviving Cav1.2 as an attractive drug target to treat bladder dysfunction.

Publication: Journal Article

Yu, Weiqun. 2022. “Reviving Cav1.2 As an Attractive Drug Target to Treat Bladder Dysfunction.”. FASEB Journal 36 (1): e22118.

Dr. John C. Mathai

Person: Assistant Professor

Dr. Mathai's research interests span across areas as disparate as the biophysics of membrane transport of solutes and gases to the neural control of bladder function. He is currently investigating mechanisms of neural:bladder signaling. Using genetically engineered mice and monitoring calcium...

Laura Torre

Person: Research Assistant

Laura Torre graduated with a BS in biomedical engineering with a concentration in cell and tissue engineering from Columbia Engineering in 2024. Laura is currently a Research Assistant at Beth Israel Deaconess Medical Center working under Drs. Mathai and Zeidel on studies designed to shed light onto...

Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy.

Publication: Journal Article

Koikawa, Kazuhiro, Shin Kibe, Futoshi Suizu, Nobufumi Sekino, Nami Kim, Theresa D Manz, Benika J Pinch, et al. 2021. “Targeting Pin1 Renders Pancreatic Cancer Eradicable by Synergizing With Immunochemotherapy.”. Cell 184 (18): 4753-4771.e27.

Universal promoter scanning by Pol II during transcription initiation in Saccharomyces cerevisiae.

Publication: Journal Article

Qiu, Chenxi, Huiyan Jin, Irina Vvedenskaya, Jordi Abante Llenas, Tingting Zhao, Indranil Malik, Alex M Visbisky, et al. 2020. “Universal Promoter Scanning by Pol II During Transcription Initiation in Saccharomyces Cerevisiae.”. Genome Biology 21 (1): 132.

The role of the Pin1-cis P-tau axis in the development and treatment of vascular contribution to cognitive impairment and dementia and preeclampsia.

Publication: Journal Article

Qiu, Chenxi, Zhixiong Li, David A Leigh, Bingbing Duan, Joseph E Stucky, Nami Kim, George Xie, Kun Ping Lu, and Xiao Zhen Zhou. 2024. “The Role of the Pin1-Cis P-Tau Axis in the Development and Treatment of Vascular Contribution to Cognitive Impairment and Dementia and Preeclampsia.”. Frontiers in Cell and Developmental Biology 12: 1343962.

Structural basis of transcription: RNA polymerase II substrate binding and metal coordination using a free-electron laser.

Publication: Journal Article

Lin, Guowu, Christopher O Barnes, Simon Weiss, Bercem Dutagaci, Chenxi Qiu, Michael Feig, Jihnu Song, et al. 2024. “Structural Basis of Transcription: RNA Polymerase II Substrate Binding and Metal Coordination Using a Free-Electron Laser.”. Proceedings of the National Academy of Sciences of the United States of America 121 (36): e2318527121.

Characterization of RNA polymerase II trigger loop mutations using molecular dynamics simulations and machine learning.

Publication: Journal Article

Dutagaci, Bercem, Bingbing Duan, Chenxi Qiu, Craig D Kaplan, and Michael Feig. 2023. “Characterization of RNA Polymerase II Trigger Loop Mutations Using Molecular Dynamics Simulations and Machine Learning.”. PLoS Computational Biology 19 (3): e1010999.