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Prolonging parathyroid hormone analog action in vitro and in vivo through peptide lipidation.

Publication: Journal Article

Höppner, Jakob, Hiroshi Noda, Anju Krishnan Anitha, Ross W Cheloha, Thomas Dean, Michael Bruce, Daniel J Brooks, et al. 2025. “Prolonging Parathyroid Hormone Analog Action in Vitro and in Vivo through Peptide Lipidation.”. Nature Communications 16 (1): 4487.

Model for Musculoskeletal Injury Risk Factors Among US Army Basic Combat Trainees.

Publication: Journal Article

Foulis, Stephen A, Susan P Proctor, Barry A Spiering, Leila A Walker, Katelyn Guerriere Aaron, Colleen M Castellani, Ian M Hussian, et al. 2025. “Model for Musculoskeletal Injury Risk Factors Among US Army Basic Combat Trainees.”. JAMA Network Open 8 (6): e2513177.

The relationship between fall risk, trochanteric soft tissue thickness, and hip fracture risk in older adults.

Publication: Journal Article

Johannesdottir, Fjola, Thor Aspelund, Sarah Mahar, Sigurdur Sigurdsson, Vilmundur Gudnason, and Mary L Bouxsein. 2025. “The Relationship Between Fall Risk, Trochanteric Soft Tissue Thickness, and Hip Fracture Risk in Older Adults.”. Journal of Bone and Mineral Research : The Official Journal of the American Society for Bone and Mineral Research.

Isabel Barnet

Person: Medical Student (Harvard Medical School)

Advancing a new regulatory pathway for conduct of osteoporosis clinical trials

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One in two women and one in four men over the age of 50 will suffer a fragility fracture in their remaining lifetime. These fractures lead to profound morbidity, increased mortality and high personal and societal costs. While effective treatments are available, they do not prevent all fractures and...

Beyond BMD and FRAX: Potential for improving hip fracture prediction with bone microstructure measures.

Publication: Journal Article

Johannesdottir, Fjola, and Mary L Bouxsein. 2025. “Beyond BMD and FRAX: Potential for Improving Hip Fracture Prediction With Bone Microstructure Measures.”. Journal of Bone and Mineral Research : The Official Journal of the American Society for Bone and Mineral Research.

Opportunistic Screening on Chest CT, From the AJR Special Series on Screening.

Publication: Journal Article

Theure, Konstantin L, Lea Mantz, Sadia Sultana, Louise M Henderson, Lori C Sakoda, Ella Kazerooni, Raúl San José Estépar, Mary L Bouxsein, and Florian J Fintelmann. 2025. “Opportunistic Screening on Chest CT, From the AJR Special Series on Screening.”. AJR. American Journal of Roentgenology.

Treatment of children and adults with X-linked hypophosphatemia with calcitriol alone: A prospective open label study.

Publication: Journal Article

Mitchell, Deborah, Mackenzie Jordan, Sarah Gehman, Sara Rudolph, Harald Jüppner, Madhusmita Misra, Thomas Thacher, et al. 2025. “Treatment of Children and Adults With X-Linked Hypophosphatemia With Calcitriol Alone: A Prospective Open Label Study.”. The Journal of Clinical Endocrinology and Metabolism.

Long-duration type 1 diabetes is associated with deficient cortical bone mechanical behavior and altered matrix composition in human femoral bone.

Publication: Journal Article

Emerzian, Shannon R, Jarred Chow, Ramina Behzad, Mustafa Unal, Daniel J Brooks, I-Hsien Wu, John Gauthier, et al. 2024. “Long-Duration Type 1 Diabetes Is Associated With Deficient Cortical Bone Mechanical Behavior and Altered Matrix Composition in Human Femoral Bone.”. Journal of Bone and Mineral Research : The Official Journal of the American Society for Bone and Mineral Research 40 (1): 87-99.

Advanced imaging techniques for assessing skeletal fragility

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Osteoporosis remains underdiagnosed and undertreated. Current clinical standards have low sensitivity because half of all fracturesoccur in individuals without osteoporosis based on bone density testing and/or with few clinical risk factors. Photon-counting computed tomography (PCCT) is an emerging...