Therapeutic advances in alcohol-associated hepatitis.
Szabo, Gyongyi, Mark Thursz, and Vijay H Shah. 2022. “Therapeutic Advances in Alcohol-Associated Hepatitis.”. Journal of Hepatology 76 (6): 1279-90.
Search
Search results
131 results found
Granulocyte colony-stimulating factor attenuates liver damage by M2 macrophage polarization and hepatocyte proliferation in alcoholic hepatitis in mice.
Cho, Yeonhee, Radhika Joshi, Patrick Lowe, Christopher Copeland, Marcelle Ribeiro, Caroline Morel, Donna Catalano, and Gyongyi Szabo. 2022. “Granulocyte Colony-Stimulating Factor Attenuates Liver Damage by M2 Macrophage Polarization and Hepatocyte Proliferation in Alcoholic Hepatitis in Mice.”. Hepatology Communications 6 (9): 2322-39.
A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients.
Pita-Juárez, Yered, Dimitra Karagkouni, Nikolaos Kalavros, Johannes C Melms, Sebastian Niezen, Toni M Delorey, Adam L Essene, et al. 2022. “A Single-Nucleus and Spatial Transcriptomic Atlas of the COVID-19 Liver Reveals Topological, Functional, and Regenerative Organ Disruption in Patients.”. BioRxiv : The Preprint Server for Biology.
The Beneficial Effects of Lactobacillus GG Therapy on Liver and Drinking Assessments in Patients with Moderate Alcohol-Associated Hepatitis.
Vatsalya, Vatsalya, Wenke Feng, Maiying Kong, Huirong Hu, Gyongyi Szabo, Arthur McCullough, Srinivasan Dasarathy, et al. 2023. “The Beneficial Effects of Lactobacillus GG Therapy on Liver and Drinking Assessments in Patients With Moderate Alcohol-Associated Hepatitis.”. The American Journal of Gastroenterology 118 (8): 1457-60.
Protective role of cGAS in NASH is related to the maintenance of intestinal homeostasis.
Ribeiro, Marcelle de Carvalho, Yeonhee Cho, Jeeval Mehta, Xiaojing Wang, Mrigya Babuta, Christopher Copeland, Hosni Hussein, Donna Catalano, Yanbo Wang, and Gyongyi Szabo. 2023. “Protective Role of CGAS in NASH Is Related to the Maintenance of Intestinal Homeostasis.”. Liver International : Official Journal of the International Association for the Study of the Liver 43 (9): 1937-49.
Therapeutic inhibition of miR-155 attenuates liver fibrosis via STAT3 signaling.
Bala, Shashi, Yuan Zhuang, Prashanth Thevkar Nagesh, Donna Catalano, Adam Zivny, Yanbo Wang, Jun Xie, Guangping Gao, and Gyongyi Szabo. 2023. “Therapeutic Inhibition of MiR-155 Attenuates Liver Fibrosis via STAT3 Signaling.”. Molecular Therapy. Nucleic Acids 33: 413-27.
Safety, Pharmacokinetics, and Efficacy Signals of Larsucosterol (DUR-928) in Alcohol-Associated Hepatitis.
Hassanein, Tarek, Craig J McClain, Vatsalya Vatsalya, Lance L Stein, Steven L Flamm, Paul Martin, Matthew C Cave, et al. 2024. “Safety, Pharmacokinetics, and Efficacy Signals of Larsucosterol (DUR-928) in Alcohol-Associated Hepatitis.”. The American Journal of Gastroenterology 119 (1): 107-15.
Reply: Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation.
Ribeiro, Marcelle de Carvalho, Mrigya Babuta, and Gyongyi Szabo. 2024. “Reply: Alcohol-Induced Extracellular ASC Specks Perpetuate Liver Inflammation and Damage in Alcohol-Associated Hepatitis Even After Alcohol Cessation.”. Hepatology (Baltimore, Md.) 79 (2): E28-E29.
IRF3 regulates neuroinflammatory responses and the expression of genes associated with Alzheimer's disease.
Joshi, Radhika, Veronika Brezani, Gabrielle M Mey, Sergi Guixé-Muntet, Martí Ortega-Ribera, Yuan Zhuang, Adam Zivny, Sebastian Werneburg, Jordi Gracia-Sancho, and Gyongyi Szabo. 2024. “IRF3 Regulates Neuroinflammatory Responses and the Expression of Genes Associated With Alzheimer’s Disease.”. BioRxiv : The Preprint Server for Biology.
Randomized trial of anakinra plus zinc vs. prednisone for severe alcohol-associated hepatitis.
Gawrieh, Samer, Srinivasan Dasarathy, Wanzhu Tu, Patrick S Kamath, Naga P Chalasani, Craig J McClain, Ramon Bataller, et al. 2024. “Randomized Trial of Anakinra Plus Zinc Vs. Prednisone for Severe Alcohol-Associated Hepatitis.”. Journal of Hepatology 80 (5): 684-93.