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We are delighted to welcome our newest team member, Yangmian Yuan, who joins us as a postdoctoral research fellow. Yangmian recently earned her PhD from the College of Life Sciences at Wuhan University, China, with a dissertation focusing on adipose tissue energy metabolism.

Evan wrote a comprehensive review article on interferon regulatory factors (IRFs) in metabolism, with help from Zunair Ahmad and Wahab Kahloan. It just came out in Nature Reviews Endocrinology.

Congratulations to Shuai Yan — his paper was just published in Nature Communications. Shuai showed that IRF3 causes insulin resistance in adipocytes independent of any effect on body weight. The mechanism is via induction of an enzyme called AIG1, which encodes a hydrolase that destroys insulin...

Greg’s latest paper is available on BioRxiv. Using unique intra-patient controls, he shows that the adipose tissue of chronic lymphedema has a different complement of adipose stromal and progenitor cells (ASPCs), which confer a more pro-adipogenic and pro-lymphangiogenic environment. https://www...

Please check out the new paper from the Rosen lab (working in collaboration with Randy Seeley’s group at the University of Michigan) about changes in adipose tissue after two different weight loss strategies in mice. Margo Emont compared white adipose tissue from obese mice that received either...

The Rosen Lab is bidding a fond farewell to Greg Westcott and Winnie Zhang as 2025 draws to a close. Greg’s leadership has been instrumental in advancing our knowledge on lymphedema, while Winnie’s tenacity have been the driving force in bringing the IRS1 project to a successful completion. It has...