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Research

The “ National Center for Functional Glycomics” ( NCFG) as a National Resource Center is devoted to the technology of glycan recognition through microarray display and other modes of glycan presentation. This Center is the first of its kind with the central focus being exploration of the functional...

Technology Research and Development (TR&Ds)

The NCFG operates under 3 TR&D projects: Project 1 – Expansion of Glycan Microarray Technology Project 2 – Shotgun Glycomics and Functional Recognition Project 3 – Glycan Display and Recognition TR&D project goals will focus on 5 main areas and the projects integrates and synergizes with each other...

Protocols

Array Protocols- Reusing Glycan Microarray Slides Using MAWE Direct Binding Assay + MAWE Protocol Glycan Binding Assay with Biotin-tagged Sample + MAWE Unlabeled Monoclonal Antibody + MAWE Glycan Binding Assay with tagged Sample on CFG Slides + MAWE Tertiary Binding Assay for Unlabeled sample and...

Activities

The National Center for Functional Glycomics (NCFG) is comprised of a Center Director, project leaders, project coordinator, administration, postdocs, graduate students, and laboratory research staff. There is an External Advisory Committee that helps to guide the center in achieving its goals...

Background Information

Glycoscience is the broad study of the chemical structures and biological functions of complex glycoconjugates and encompasses the specialized areas of glycomics and glycobiology. The area is relatively new, but interest is rapidly growing due to the recent explosion of information about the...

Useful Links

Essentials of Glycobiology 4th Edition (Book) (Open Access) NIH Pubmed Harvard Medical School Center for Glycoscience GlyGen KEGG Glycan Congenital Disorders of Glycosylation CAZy Carbohydrate Active Enzymes Predicting O-glycosylation Sites GLYCO3D CarbBank Complex Carbohydrate Research Center at...

Reagents

These reagents are made available through the BIDMC Glycomics Core for fees for shipping and handling only. For the latest reagent shipping and handling fees please see https://www.bidmc.org/research/core-facilities/glycomics-core/fees Please email glycomicscore@bidmc.harvard.edu for all inquiries...