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By: Richard D. Cummings L-Ascorbic acid, vitamin C, is termed a ‘sugar acid’ or ‘acidic sugar’, and is a derivative of glucose with a carboxyl group at C1 (1). In mammals, UDP-glucuronic acid is the source of D-glucuronic acid, the precursor to vitamin C (2). Vitamin C is sometimes referred to as a...

By: Richard D. Cummings Cholesterol can be glycosylated, and indeed glucosylated cholesterol is common (1). In animal cells, it is a β-D-glucopyranoside derivative of cholesterol (GlcChol), which is generated through a ‘transglycosylation’ pathway in the lysosomes, by the enzymes glucocerebrosidase...