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16] Facts About: Major Glycoprotein in Urine – Uromodulin/Tamm-Horsfall Protein (THP)

Blog: February 03, 2025

By: Richard D. Cummings The major urinary glycoprotein is the Tamm-Horsfall protein (THP), also named uromodulin (Umod), and encoded by UMOD (1-4). Its concentration in urine can be as high as 1-2 mg/mL. It was discovered in 1950 by Tamm and Horsfall in their studies on compounds in urine that could...

Tianwei Jia

Person: Postdoctoral Research Fellow

Dr. Jia earned his Master's in Medicinal Chemistry in 2018 from Tianjin University of Science and Technology, working under the guidance of Prof. Yu Peng. His master’s research concentrated on the synthesis and characterization of glycol-nanoparticles, serving as probes to explore carbohydrate...

Kelsey M Charon

Person: Research Assistant

Kelsey received her bachelor's in Biological Engineering with a minor in Chemistry from Wentworth Institute of Technology (August 2023). As a Massachusetts native, she has been living and studying in Boston for the last several years. She has worked on projects with synthetic biology and cell...

Glycan Binding Assay with Biotin-tagged Sample + MAWE

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1. Introduction: 1.1. Primary objective is to determine the binding specificity of Glycan Binding Proteins (GBPs) and organisms submitted by investigators, using the printed glycan microarray platform. Removal of binding with the MAWE method, for future reuse of the slide. 2. References: 2.1. https...