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Thiamine as adjunctive therapy for diabetic ketoacidosis (DKAT) trial protocol and statistical analysis plan: a prospective, single-centre, double-blind, randomised, placebo-controlled clinical trial in the USA.

Vine, Jacob, Shivani Mehta, Lakshman Balaji, Katherine M Berg, Noa Berlin, Xiaowen Liu, Long Ngo, et al. 2024. “Thiamine As Adjunctive Therapy for Diabetic Ketoacidosis (DKAT) Trial Protocol and Statistical Analysis Plan: A Prospective, Single-Centre, Double-Blind, Randomised, Placebo-Controlled Clinical Trial in the USA.”. BMJ Open 14 (2): e077586.

Program in Placebo Studies

For many years, the placebo effect was considered to be no more than a nuisance variable that needed to be controlled in clinical trials. Only recently have researchers redefined it as the key to understanding the healing that arises from medical ritual, the context of treatment, the patient...

Sigall K. Bell, MD

Research Concentrations Transparency Patient Safety Professional Biography Sigall Bell, MD, is a physician-researcher, healthcare innovator, and associate professor of medicine at Harvard Medical School. As Director of Patient Safety and Discovery at OpenNotes at Beth Israel Deaconess Medical Center...

Janice D. Walker, RN, MBA

Research Concentrations Patient Perspectives on Quality of Care Patient-Facing Health Information Technology Professional Biography Jan Walker's principal research interests lie in patients' perspectives on care and the use of information technologies to improve their experience. She and Tom...