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Targeted nanotherapy for kidney diseases: a comprehensive review
Sabiu, G., V. Kasinath, S. Jung, X. Li, G. C. Tsokos, and R. Abdi. 2023. “Targeted Nanotherapy for Kidney Diseases: A Comprehensive Review”. Nephrol Dial Transplant 38: 1385-96.
Inhibition of calcium/calmodulin-dependent protein kinase IV in arthritis: dual effect on Th17 cell activation and osteoclastogenesis
Koga, T., M. Umeda, N. Yoshida, A. Satyam, M. Jha, M. Scherlinger, R. Bhargava, et al. 2023. “Inhibition of Calcium/Calmodulin-Dependent Protein Kinase IV in Arthritis: Dual Effect on Th17 Cell Activation and Osteoclastogenesis”. Rheumatology (Oxford) 62: 861-71.
Efficacy and Safety of Ustekinumab in Patients With Active Systemic Lupus Erythematosus: Results of a Phase II Open-label Extension Study
van Vollenhoven, R. F., B. H. Hahn, G. C. Tsokos, P. Lipsky, R. M. Gordon, K. Fei, K. H. Lo, et al. 2022. “Efficacy and Safety of Ustekinumab in Patients With Active Systemic Lupus Erythematosus: Results of a Phase II Open-Label Extension Study”. J Rheumatol 49: 380-87.
Engineered T cells to treat lupus arrive on the scene
Tsokos, G. C. 2022. “Engineered T Cells to Treat Lupus Arrive on the Scene”. Nature 611: 456-58.
Intertwined pathways of complement activation command the pathogenesis of lupus nephritis
Satyam, A., R. Hisada, R. Bhargava, M. G. Tsokos, and G. C. Tsokos. 2022. “Intertwined Pathways of Complement Activation Command the Pathogenesis of Lupus Nephritis”. Transl Res 245: 18-29.
CD38 reduces mitochondrial fitness and cytotoxic T cell response against viral infection in lupus patients by suppressing mitophagy
Chen, P. M., E. Katsuyama, A. Satyam, H. Li, J. Rubio, S. Jung, S. Andrzejewski, et al. 2022. “CD38 Reduces Mitochondrial Fitness and Cytotoxic T Cell Response Against Viral Infection in Lupus Patients by Suppressing Mitophagy”. Sci Adv 8: eabo4271.
Ikaros, Aiolos and other moving targets to treat SLE
Boulougoura, A., and G. C. Tsokos. 2022. “Ikaros, Aiolos and Other Moving Targets to Treat SLE”. Nat Rev Rheumatol 18: 499-500.
ADAM9 enhances Th17 cell differentiation and autoimmunity by activating TGF-beta1
Umeda, M., N. Yoshida, R. Hisada, C. Burbano, S. Y. K. Orite, M. Kono, V. C. Kyttaris, S. Krishfield, C. A. Owen, and G. C. Tsokos. 2021. “ADAM9 Enhances Th17 Cell Differentiation and Autoimmunity by Activating TGF-Beta1”. Proc Natl Acad Sci U S A 118.
Glutathione peroxidase 4-regulated neutrophil ferroptosis induces systemic autoimmunity
Li, P., M. Jiang, K. Li, H. Li, Y. Zhou, X. Xiao, Y. Xu, et al. 2021. “Glutathione Peroxidase 4-Regulated Neutrophil Ferroptosis Induces Systemic Autoimmunity”. Nat Immunol 22: 1107-17.