Search

Highly Cited Research from the Core Many discoveries have relied upon careful measurement of body composition and metabolic rates in un-anesthetized, freely moving mice. One metric to determine the impact of a scientific publication is how many times other scientific articles have referred to that...

PARR Instruments Bomb Calorimeter Determines energy content of food or fecal matter FLIR Thermal Imaging Camera Determines thermal radiation Environmental Chamber Controls ambient temperature and environmental conditions CGM (Continuous Glucose Monitoring) Telemetry System Continuously monitors...

Indirect calorimetry data for one mouse implanted with a glucose and body temperature telemetry probe in the Promethion indirect calorimeter. Food was removed 1 h before start of the dark photoperiod (grey) and mice enter bouts of torpor (Rubio et al., Mol Metabolism, 2023)​

Germ-free mice can be examined using isolator cages (bottom). With this approach, we canexamine the metabolic profile of germ-free mice or mice colonized with specific microbes. ​

Thermal imaging was performed using FLIR on juvenile mice placed in a sterile 6-well culture dish to visualize body temperature distribution.

Body composition was measured using the Echo MRI 3-in-1 system and plotted in CalR, with fat, lean, and total mass shown on the left and corresponding percentage composition on the right. ​

Indirect calorimetry data for one mouse implanted with a glucose and body temperature telemetry probe in the Promethion indirect calorimeter (Rubio et al., Mol Metabolism, 2023)​

EchoMRI 3-in-1 Body Composition Analyzer Measures live mice up to 100g, tissue samples (including Zebrafish) of 10g, and biopsy samples up to 0.1g Measurements include lean mass, fat mass, and water mass 5 minutes per mouse No anesthesia required

Optogenetic stimulation of Agrp neurons in ChR2-expressing mice was performed in the Promethion calorimeter, with food intake, metabolic rate, body temperature, and activity measured during the stimulation period.

​ Male C57Bl/6J mice housed at thermoneutrality were administered the β-adrenergic agonist CL 316,243, and changes in oxygen consumption were continuously measured.