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Because EM projects can be extensive and expensive, the EM Core Facility invites all researchers to meet with core staff before a project is started to discuss the scope of the project, how to procure and fix tissues, time line, budgetary concerns, and any other general issues which might arise...

Provides Services in Electron Microscopy The EM Core at BIDMC provides service, technical assistance, and instrumentation for electron microscopy techniques. Tissue processing for Transmission Electron Microscopy Sectioning for Transmission Electron Microscopy Ultrastructural analysis and image...

Work is done on a fee-for-service basis with a graded fee structure. Priority use is given to BIDMC researchers and priority use and reduced fees are provided to investigators of the Harvard Digestive Diseases Center (due to the NIH-funded Digestive Diseases Center grant).

Related Links: BIDMC Histology Core BIDMC Immunostaining and Microscopy Core Harvard Digestive Disease Center (HDDC) Dana-Farber/Harvard Cancer Center Rodent Histopathology Core * Please note that this website is designed for NIEHS-core users to apply for pilot projects grant. Others may use this...

Equipment in the Facility Includes: JEOL 1400 (photo, right) Installed January 2010 and is state-of-the-art. 120kV High contrast Gatan Orius 11 MegaPixel CCD Cameras for photodocumentation SerialEM, IMOD, and Chimera EM Tomography software. Leica Ultracut E Ultramicrotome Leica Glass Knife Breaker...

Routine EM Services Consultation Tissue Preparation Tissue Processing Thick/Thin Sectioning Contrast Staining Service or Independent use of the electron microscope. Image Analysis