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Beneficial metabolic effects of PAHSAs depend on the gut microbiota in diet-induced obese mice but not in chow-fed mice.

Publication: Journal Article
Lee, Jennifer, Kerry Wellenstein, Ali Rahnavard, Andrew T Nelson, Marlena M Holter, Bethany P Cummings, Vladimir Yeliseyev, et al. 2024. “Beneficial Metabolic Effects of PAHSAs Depend on the Gut Microbiota in Diet-Induced Obese Mice But Not in Chow-Fed Mice.”. Proceedings of the National Academy of Sciences of the United States of America 121 (28): e2318691121.

Jennifer Lee, PhD

she/her
Person: Scientist II, Metabolism & Basic Biology of Aging, Jean Mayer USDA Human Nutrition Research Center for Aging, Tufts University | Boston, MA, Assistant Research Professor, Tufts University School of Medicine | Boston, MA
Tufts University profile

Tsugumichi Saito, MD, PhD

he/him
Person: Physician/Researcher, Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine | Maebashi, Japan

Christine Huppertz, PhD

she/her
Person: Senior Principal Scientist, Novartis Institutes for Biomedical Research | Basel, Switzerland

Peng Zhou, PhD

he/him
Person: Director of Translational Research, NervGen Pharma Corp | Greater Boston, MA

Regan Roat, MD, PhD

she/her
Person: Staff Physician, Adult Diabetes and Diabetes in Pregnancy, Joslin Diabetes Center/ Beth Israel Lahey Health, Teaching Affiliate of Harvard Medical School and Staff Endocrinologist at Atrius Health | Boston, MA

Interviews

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March 2025 - Endocrine News interview (PDF) March 2025 - Women's Interprofessional Network of the American Diabetes Association (WIN ADA) interview (video) March 2020 - The Journal of Clinical Investigation (JCI), Conversations with Giants in Medicine: Barbara Kahn (video and PDF) Aug 2016 - Cell...

Sanam Dharma, PhD

she/her
Person: Postdoctoral Fellow
Studying a novel class of endogenous mammalian lipids called branched fatty acid esters of hydroxy fatty acids (FAHFA).