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Lab email: SISL@bidmc.harvard.edu Sleep and Inflammatory Systems Laboratory Department of Neurology Beth Israel Deaconess Medical Center Harvard Medical School 330 Brookline Avenue, Dana 735 Boston, MA 02215

Microarray resources currently offered: Name (Click Name for List) Description Availability Reference QC Data Defined Glycan Microarrays Known, defined glycan structures CFG Glycan microarray * Diverse mammalian-type glycan array with N- and O-glycans on NHS slides Yes upon request. CFG Request. CFG...

Algorithm guides treatment of bacterial keratitis, reduces costs Culturing all suspected cases of bacterial eye infection can be costly, time consuming, and often unnecessary. A new algorithm developed at Mass. Eye and Ear, consisting of a simple set of rules, now helps clinicians in the Emergency...

Software tools and resources developed by the NCFG: GLAD - a tool to visualize, analyze and compare glycan microarray data for exploratory data analysis. GlycoGlyph - An open source glycan drawing, visualizing and naming application. Allows you to draw glycans in SNFG format and obtain names in CFG...

Where clinicians, researchers, educators, and industry leaders come together to collaborate and discover new life-changing cures. The Harvard Ophthalmology Centers of Excellence and Institutes are multidisciplinary collaborations that unite clinicians, educators, investigators, trainees, and...

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The goal of this project is to investigate two processes underlying increased pain vulnerability in the course of repeated exposure to insomnia: (1) Sensitization of the nociceptive system due to a progressive increase of the inflammatory response and (2) Decreased habituation to pain due to a...

The primary goal of this project is to gather preliminary support for the hypothesis that deficient sleep leads to pain amplification through an inflammatory mechanism while the secondary goal is to investigate the potential mechanisms contributing to blood pressure reduction in response to aspirin...

The extraordinary growth and specialization of the sciences over the past several decades has made it increasingly difficult to link the divide between clinical and basic science components of ophthalmic and vision sciences. The less-than-optimal degree of cross-talk between scientists engaged in...

This project gathered preliminary data to test the hypothesis that sleep maintenance insomnia is associated with a stronger activation of stress response systems compared to sleep onset insomnia. Sleep Research Society Foundation [PI: Monika Haack] 10/01/2010 - 09/30/2012