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The March Toward Improved Heart Failure Outcomes Requires an Emphasis on Affordability.

Publication: Journal Article

Foote, Julia H A, and Dhruv S Kazi. 2024. “The March Toward Improved Heart Failure Outcomes Requires An Emphasis on Affordability.”. JACC. Heart Failure 12 (7): 1238-41.

Insights Derived from the Synthesis of a Complex Core 2 Glycan.

Publication: Journal Article

Dhakal, Bibek, Appi Mandhapati, Simon Park, Lijun Sun, and Elliot L Chaikof. 2024. “Insights Derived from the Synthesis of a Complex Core 2 Glycan.”. The Journal of Organic Chemistry 89 (16): 11641-58.

Design and synthesis of emodin derivatives as novel inhibitors of ATP-citrate lyase.

Publication: Journal Article

Koerner, Steffi K, Jun-Ichi Hanai, Sha Bai, Finith E Jernigan, Miwa Oki, Chieko Komaba, Emi Shuto, Vikas P Sukhatme, and Lijun Sun. 2017. “Design and Synthesis of Emodin Derivatives As Novel Inhibitors of ATP-Citrate Lyase.”. European Journal of Medicinal Chemistry 126: 920-28.

Novel indolyl-chalcones target stathmin to induce cancer cell death.

Publication: Journal Article

Wegiel, Barbara, Yiqiang Wang, Mailin Li, Finith Jernigan, and Lijun Sun. 2016. “Novel Indolyl-Chalcones Target Stathmin to Induce Cancer Cell Death.”. Cell Cycle (Georgetown, Tex.) 15 (9): 1288-94.

Meihan (Rosie) Guo

Person: Postdoctoral Research Fellow

Hometown: Jilin, China Education/background: University of Hong Kong, Integrative cardiovascular physiology, PhD; University of Worcester, Exercise physiology, BSc (1st class Hons) Years in the lab: 1 month Rosie is working with Dr. Ho and Dr. Robbins to study cardiovascular, hematological, and...

Synthesis, crystallographic characterization and electrochemical property of a copper(II) complex of the anticancer agent elesclomol.

Publication: Journal Article

Vo, Nha Huu, Zhiqiang Xia, Jason Hanko, Tong Yun, Steve Bloom, Jianhua Shen, Keizo Koya, Lijun Sun, and Shoujun Chen. 2014. “Synthesis, Crystallographic Characterization and Electrochemical Property of a Copper(II) Complex of the Anticancer Agent Elesclomol.”. Journal of Inorganic Biochemistry 130: 69-73.

Indole- and indolizine-glyoxylamides displaying cytotoxicity against multidrug resistant cancer cell lines.

Publication: Journal Article

James, David A, Keizo Koya, Hao Li, Guiqing Liang, Zhiqiang Xia, Weiwen Ying, Yaming Wu, and Lijun Sun. 2008. “Indole- and Indolizine-Glyoxylamides Displaying Cytotoxicity Against Multidrug Resistant Cancer Cell Lines.”. Bioorganic & Medicinal Chemistry Letters 18 (6): 1784-7.

2024 BIDMC Annual Research Retreat

News: September 05, 2024

Simon Lab members attended the research retreat. Alejandra and Emily presented "Pharmacological stabilization of the retromer complex results in the reduction of α-synuclein accumulation and in the control of α-synuclein clearance pathways" and joined in conversations about the latest research at...

PGC-1α

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Extracellular vesicles show promise for cancer theranostics.

Publication: Journal Article

Segal, Meirav, and Frank J Slack. 2019. “Extracellular Vesicles Show Promise for Cancer Theranostics.”. Annals of Translational Medicine 7 (7): 158.