Search
Search results
127 results found
Dejahni Tripp
New Publication - Congratulations Dr Radhika Joshi (Postdoctoral fellow) on her publication in the Journal of Neuroinflammation, August 2024
Joshi, R., Brezani, V., Mey, G.M. et al. IRF3 regulates neuroinflammatory responses and the expression of genes associated with Alzheimer’s disease. J Neuroinflammation 21, 212 (2024). https://doi.org/10.1186/s12974-024-03203-7.
New Publication - Congratulations Dr Prashanth Thevkar Nagesh (Instructor) on his publication in the Science Translational Medicine Journal, August 2024
Nagesh PT, Cho Y, Zhuang Y, Babuta M, Ortega-Ribera M, Joshi R, Brezani V, Patel A, Datta AA, Brezani V, Hsieh Y, Ramos A, Mehta J, Copeland C, Kanata E, Jiang ZG, Vlachos I, Asara J, AlcHepNet Clinical Centers Investigators, Szabo G. In vivo Bruton’s tyrosine kinase inhibition attenuates alcohol...
Awards - Congratulations Dr Marti Ortega Ribera (Postdoctoral fellow) on winning 'Best Poster' in Basic Science category at the BIDMC Research retreat, September 2024
Graduate Students
Neuroinflammation and Aging
Neuroinflammation and Alzheimer’s disease The pathological role of interferon signaling is emerging in neuroinflammatory disorders, yet, the specific role of Interferon Regulatory Factor 3 (IRF3) in neuroinflammation remains poorly understood. Here, we show that global IRF3 deficiency delays TLR4...
Contact US
Gyongyi Szabo, MD, PhD, FAASLD, AGAF, FACP Mitchell T. Rabkin, M.D. Chair Professor of Medicine and Faculty Dean for Academic Affairs Harvard Medical School Chief Academic Officer Beth Israel Lahey Health and Beth Israel Deaconess Medical Center Email: gszabo1@bidmc.harvard.edu Executive Assistant...
Research
In our laboratory, we study mechanisms of innate immune activation in liver diseases and its role on modulation of liver parenchymal cells including hepatocytes and stellate cells. We employ a broad range of preclinical murine liver injury models of alcohol-associated hepatitis, metabolic...
Biomarkers
Biomarkers in Liver Disease We are exploring novel therapies and biomarker discoveries in AH. Direct effects of alcohol on hepatocytes, increased intestinal permeability and activation of innate immune system (Kupffer cells) by gut-derived LPS are major factors in AH leading to over-activation of...