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Fred Alt, PhD Boston Children's Hospital Charlie Serhan, PhD Brigham and Women's Hospital Mark Zeidel, MD Beth Israel Deaconness Medical Center David Golan, MD, PhD Harvard Medical School

This project investigated the effects of repeated cycles of short sleep duration on vascular functioning and levels of inflammatory and adhesion molecules in peripheral circulation in healthy participants in order to determine if sleep is essential for homeostasis of multiple host defense mechanisms...

The goal of this study is to test the hypothesis that repeated exposure to cycles of insufficient sleep increases susceptibility to a variety of disease states by progressively compromising the integrity of stress response systems. We will test whether the hypothalamic-pituitary, sympatho-adrenal...

Cerebrovascular Risk, Aging, and Their Effects on the Brain Changes in memory, thinking, and organizational skills occur in the course of normal aging, but can sometimes indicate an underlying disease. These changes in thinking ability can occur as a result of medical conditions (such as high blood...

Overview of HDDC Cores and Services Use the links for detailed descriptions, locations and contact information. Biomedical CORE B: Microscopy and Histopathology Histology(paraffin and frozen sections) Electron and Confocal Microscopy Photodocumentation and Widefield Microscopy Advanced Imaging...

Core Technician: Sierra Anderson Services Polarized epithelial cell lines maintained and available: human intestinal T84, HT29, Caco2-BBe, and SKCO-15; canine renal MDCK I and MDCK II cells; porcine kidney LL-CPK cells Second site storage available for specialized cell lines prepared by HDDC members...