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My lab, along with the Saper group, is dedicated to advancing research in sleep and respiration, with a particular emphasis on the neural circuits involved in sleep, narcolepsy, sleep homeostasis, sleep deprivation, pain, and apnea-induced arousals. Our research employs state-of-the-art techniques...

Prior studies identify brain/spinal cord regions involved in controlling bladder function, but often do not resolve neuronal subpopulations or their specific connections. We seek to develop in mice a complete circuit map of the control of bladder filling and voiding. Prior work and our own...

Analysis of diet-induced obesity experiments in male C57Bl/6J mice on a low-fat diet (LFD) or high-fat diet (HFD), demonstrating differences in body weight, energy intake, expenditure, and balance (Banks et al., Nature Metabolism, 2025). ​

Optogenetic stimulation of Agrp neurons in ChR2-expressing mice was performed in the Promethion calorimeter, with food intake, metabolic rate, body temperature, and activity measured during the stimulation period.

Type 2 diabetes is one of obesity’s most tightly linked comorbidities, and its prevalence is rising in parallel with the global obesity epidemic. Uncontrolled obesity often leads to insulin resistance, beta cell failure, and hyperglycemia. Although effective, many glucose-lowering agents circumvent...

Dr. Aronson is the Primary Investigator of the laboratory and serves as an attending neurosurgeon and Director of Epilepsy Surgery at Beth Israel Deaconess Medical Center. He has an appointment as Assistant Professor of Neurosurgery at Harvard Medical School. He graduated from the Massachusetts...

We are an interdisciplinary research team led by psychiatrist Matcheri Keshavan, MD and sociologist Russell Schutt, PhD in the Department of Psychiatry, Beth Israel Deaconess Medical Center and the Harvard Medical School. Our co-investigators are distinguished researchers from our own department and...

Aplanatic solid immersion lens (SIL) microscopy is required to achieve the highest possible resolution for next generation silicon IC backside inspection and failure analysis. However, aplanatic SILs are susceptible to spherical aberration introduced by substrate thickness mismatch. We have...