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Deepika Deepika
Education: Bachelors, Masters and PhD degree in Biomedical Science Research Projects: I am studying the role of MDSCs in alcohol associated liver disease and their impact on liver fibrosis. Targeting MDSCs in alcohol associated liver disease holds promise for regulating inflammation, fibrosis, and...
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Innate Immune Signaling Pathways
The pathomechanism of alcoholic liver disease (ALD) involves cumulative events such as leaky gut, hepatocyte damage and inflammation that collectively contribute to the severity of disease. Our studies have delineated the role of Toll-like receptor 4 (TLR4) signaling and identified a unique role for...
microRNAs and Extracellular Vesicles
microRNAs in Alcoholic Liver Disease Alcoholic liver disease affects millions of people worldwide and it remains to be a therapeutic challenge for clinicians. Activation of the inflammatory cascade via gut-derived lipopolysaccharide (LPS) contributes to alcoholic liver disease via induction of pro...
Alcohol-Related Liver Disease: Areas of Consensus, Unmet Needs and Opportunities for Further Study.
Szabo, Gyongyi, Patrick S Kamath, Vijay H Shah, Mark Thursz, Philippe Mathurin, and EASL-AASLD Joint Meeting. 2019. “Alcohol-Related Liver Disease: Areas of Consensus, Unmet Needs and Opportunities for Further Study.”. Hepatology (Baltimore, Md.) 69 (5): 2271-83.
Segmental Distribution of Hepatocellular Carcinoma Correlates with Microvascular Invasion in Liver Explants Undergoing Transplantation.
Al-Azzawi, Yasir, Eva Rouanet, Ryan J Hendrix, Lidia Spaho, Hesham Malik, Deepika Devuni, Gyongyi Szabo, and Graham Barnard. 2019. “Segmental Distribution of Hepatocellular Carcinoma Correlates With Microvascular Invasion in Liver Explants Undergoing Transplantation.”. Journal of Cancer Epidemiology 2019: 8534372.
Biomarkers of Macrophage Activation and Immune Danger Signals Predict Clinical Outcomes in Alcoholic Hepatitis.
Saha, Banishree, David Tornai, Karen Kodys, Adeyinka Adejumo, Patrick Lowe, Craig McClain, Mack Mitchell, et al. 2019. “Biomarkers of Macrophage Activation and Immune Danger Signals Predict Clinical Outcomes in Alcoholic Hepatitis.”. Hepatology (Baltimore, Md.) 70 (4): 1134-49.
Pathogenesis of Acute-on-Chronic Liver Failure in Patients With Infection.
Szabo, Gyongyi. 2019. “Pathogenesis of Acute-on-Chronic Liver Failure in Patients With Infection.”. Clinical Liver Disease 14 (3): 103-6.