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172 results found

Inflammasomes in chronic liver disease: Hepatic injury, fibrosis progression and systemic inflammation.

Publication: Journal Article

Taru, Vlad, Gyongyi Szabo, Wajahat Mehal, and Thomas Reiberger. 2024. “Inflammasomes in Chronic Liver Disease: Hepatic Injury, Fibrosis Progression and Systemic Inflammation.”. Journal of Hepatology.

IRF3 regulates neuroinflammatory responses and the expression of genes associated with Alzheimer's disease.

Publication: Journal Article

Joshi, Radhika, Veronika Brezani, Gabrielle M Mey, Sergi Guixé-Muntet, Martí Ortega-Ribera, Yuan Zhuang, Adam Zivny, Sebastian Werneburg, Jordi Gracia-Sancho, and Gyongyi Szabo. 2024. “IRF3 Regulates Neuroinflammatory Responses and the Expression of Genes Associated With Alzheimer’s Disease.”. Journal of Neuroinflammation 21 (1): 212.

miR-21: A therapeutic target for delaying severe liver disease and hepatocellular carcinoma in high-fat-diet-fed mice.

Publication: Journal Article

Jagtap, Urmila, Anan Quan, Yuho Ono, Jonathan Lee, Kylie A Shen, Sergei Manakov, Gyongyi Szabo, Imad Nasser, and Frank J Slack. 2024. “MiR-21: A Therapeutic Target for Delaying Severe Liver Disease and Hepatocellular Carcinoma in High-Fat-Diet-Fed Mice.”. BioRxiv : The Preprint Server for Biology.

A Novel Multi-organ Male Model of Alcohol-induced Acute-on-chronic Liver Failure Reveals NET-mediated Hepatocellular Death, Which is Prevented by RIPK3 Inhibition.

Publication: Journal Article

Ortega-Ribera, Martí, Yuan Zhuang, Mrigya Babuta, Veronika Brezani, Radhika S Joshi, Zsuzsanna Zsengeller, Prashanth Thevkar Nagesh, Yanbo Wang, Roderick Bronson, and Gyongyi Szabo. 2025. “A Novel Multi-Organ Male Model of Alcohol-Induced Acute-on-Chronic Liver Failure Reveals NET-Mediated Hepatocellular Death, Which Is Prevented by RIPK3 Inhibition.”. Cellular and Molecular Gastroenterology and Hepatology 19 (4): 101446.

Parental liver disease mortality is associated with unfavorable outcomes in patients with alcohol-associated hepatitis.

Publication: Journal Article

Tu, Wanzhu, Samer Gawrieh, Lauren Nephew, Craig McClain, Qing Tang, Srinivasan Dasarathy, Vatsalya Vatsalya, et al. 2025. “Parental Liver Disease Mortality Is Associated With Unfavorable Outcomes in Patients With Alcohol-Associated Hepatitis.”. Hepatology Communications 9 (6).

Funding

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Radhika Joshi, PhD

Person: Postdoctoral Research Fellow

Radhika Joshi, PhD Radhika is studying the mechanism of alcohol induced neuroinflammation and its effects on features of Alzheimer disease.

Hannah Seigenberg, MS, BS

Person: Alumi-Senior Clinical Research Coordinator

Education: Bachelors in Neuroscience and Psychology and Masters in Neuroscience at Tulane University. Research Projects: As the Szabo Lab’s clinical research coordinator, I work on many of the clinical and translational research projects. My main project has been the Alcoholic Hepatitis Network...

Aditi Ashish Datta, MS, BPharm

Person: Research Asistant II

Education: Bachelor’s in Pharmacy from Bombay College of Pharmacy Master’s in molecular pharmacology and toxicology from University of Southern California Research Interests: My masters research focused on investigating the dysregulation of lipid metabolism in development fatty liver disease. As a...

Mrigya Babuta, PhD

Person: Instructor

Mrigya is studying exosome biogensis and release in alcholic liver disease. She is also interested in elucidating the Type1 IFN signaling and nucleic acid signaling in alcoholic liver disease.