The emergence of SLE-causing UNC93B1 variants in 2024.
Tsokos, George C. 2024. “The Emergence of SLE-Causing UNC93B1 Variants in 2024.”. Nature Reviews. Rheumatology.
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Expanded CD8+CD38+ T Cell Population in Patients With Systemic Lupus Erythematosus Is Linked to Increased Infection Rates: A Prospective Study.
Rubio, Jose, Morgane Humbel, Lama Mulki, Eri Katsuyama, Suzanne Krishfield, Julianne O’Connell, George C Tsokos, and Vasileios Kyttaris. 2024. “Expanded CD8+CD38+ T Cell Population in Patients With Systemic Lupus Erythematosus Is Linked to Increased Infection Rates: A Prospective Study.”. ACR Open Rheumatology.
Aberrant T follicular helper cells generated by TH17 cell plasticity in the gut promote extraintestinal autoimmunity.
Fan, Tingting, Chi Tai, Kiah C Sleiman, Madeline P Cutcliffe, Haram Kim, Ye Liu, Jianying Li, et al. 2025. “Aberrant T Follicular Helper Cells Generated by TH17 Cell Plasticity in the Gut Promote Extraintestinal Autoimmunity.”. Nature Immunology 26 (5): 790-804.
Mitochondrial dysfunction drives natural killer cell dysfunction in systemic lupus erythematosus.
Fluder, Natalia W, Morgane Humbel, Emeline Recazens, Alexis A Jourdain, Camillo Ribi, George C Tsokos, and Denis Comte. 2025. “Mitochondrial Dysfunction Drives Natural Killer Cell Dysfunction in Systemic Lupus Erythematosus.”. MedRxiv : The Preprint Server for Health Sciences.
Protein phosphatases in systemic autoimmunity.
Pan, Wenliang, Maria G Tsokos, Wei Li, and George C Tsokos. 2025. “Protein Phosphatases in Systemic Autoimmunity.”. Immunometabolism (Cobham, Surrey) 7 (1): e00056.
The ubiquitin E3 ligase TRIM21 suppresses type I interferon signaling via STING degradation and ameliorates systemic autoimmunity.
Kim, Da Som, Youngjae Park, George C Tsokos, Mi- La Cho, and Seung-Ki Kwok. 2025. “The Ubiquitin E3 Ligase TRIM21 Suppresses Type I Interferon Signaling via STING Degradation and Ameliorates Systemic Autoimmunity.”. Experimental & Molecular Medicine 57 (7): 1555-66.
Curb complement to cure COVID-19
Satyam, A., and G. C. Tsokos. 2020. “Curb Complement to Cure COVID-19”. Clin Immunol 221: 108603.
TCR-alpha/beta CD4(-) CD8(-) double negative T cells arise from CD8(+) T cells
Rodriguez-Rodriguez, N., G. Flores-Mendoza, S. A. Apostolidis, F. Rosetti, G. C. Tsokos, and J. C. Crispin. 2020. “TCR-Alpha/Beta CD4(-) CD8(-) Double Negative T Cells Arise from CD8(+) T Cells”. J Leukoc Biol 108: 851-57.
Retraction Note: Microglia-dependent synapse loss in type I interferon-mediated lupus
Bialas, A. R., J. Presumey, A. Das, C. E. van der Poel, P. H. Lapchak, L. Mesin, G. Victora, et al. 2020. “Retraction Note: Microglia-Dependent Synapse Loss in Type I Interferon-Mediated Lupus”. Nature 578: 177.
Nanotargeted Delivery of Immune Therapeutics in Type 1 Diabetes
Jung, S., M. Ben Nasr, B. Bahmani, V. Usuelli, J. Zhao, G. Sabiu, A. J. Seelam, et al. 2023. “Nanotargeted Delivery of Immune Therapeutics in Type 1 Diabetes”. Adv Mater 35: e2300812.