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Total Synthesis of a PSGL-1 Glycopeptide Analogue for Targeted Inhibition of P-Selectin.

Publication: Journal Article

Dhakal, Bibek, Appi Mandhapati, Pradheep Eradi, Simon Park, Kirby Fibben, Kaicheng Li, Ashley DeYong, et al. 2024. “Total Synthesis of a PSGL-1 Glycopeptide Analogue for Targeted Inhibition of P-Selectin.”. Journal of the American Chemical Society 146 (25): 17414-27.

Indolyl-chalcone derivatives trigger apoptosis in cisplatin-resistant mesothelioma cells through aberrant tubulin polymerization and deregulation of microtubule-associated proteins.

Publication: Journal Article

Steinlein, Sophia, Frank Essmann, Amanda Franceschini Ghilardi, Heike Horn, Julia Schüler, Angelika Hausser, Lijun Sun, German Ott, and Claudia Kalla. 2023. “Indolyl-Chalcone Derivatives Trigger Apoptosis in Cisplatin-Resistant Mesothelioma Cells through Aberrant Tubulin Polymerization and Deregulation of Microtubule-Associated Proteins.”. Frontiers in Oncology 13: 1190988.

A PSGL-1 glycomimetic reduces thrombus burden without affecting hemostasis.

Publication: Journal Article

Wong, Daniel J, Diane D Park, Simon S Park, Carolyn A Haller, Jiaxuan Chen, Erbin Dai, Liying Liu, et al. 2021. “A PSGL-1 Glycomimetic Reduces Thrombus Burden Without Affecting Hemostasis.”. Blood 138 (13): 1182-93.

Discovery of furan carboxylate derivatives as novel inhibitors of ATP-citrate lyase via virtual high-throughput screening.

Publication: Journal Article

Jernigan, Finith E, Jun-Ichi Hanai, Vikas P Sukhatme, and Lijun Sun. 2017. “Discovery of Furan Carboxylate Derivatives As Novel Inhibitors of ATP-Citrate Lyase via Virtual High-Throughput Screening.”. Bioorganic & Medicinal Chemistry Letters 27 (4): 929-35.

A Cell-Based High-Throughput Screening for Inducers of Myeloid Differentiation.

Publication: Journal Article

Radomska, Hanna S, Finith Jernigan, Sohei Nakayama, Susan E Jorge, Lijun Sun, Daniel G Tenen, and Susumu S Kobayashi. 2015. “A Cell-Based High-Throughput Screening for Inducers of Myeloid Differentiation.”. Journal of Biomolecular Screening 20 (9): 1150-9.

Syntheses and antitumor activities of N'1,N'3-dialkyl-N'1,N'3-di-(alkylcarbonothioyl) malonohydrazide: the discovery of elesclomol.

Publication: Journal Article

Chen, Shoujun, Lijun Sun, Keizo Koya, Noriaki Tatsuta, Zhiqiang Xia, Timothy Korbut, Zhenjian Du, et al. 2013. “Syntheses and Antitumor Activities of N’1,N’3-Dialkyl-N’1,N’3-Di-(alkylcarbonothioyl) Malonohydrazide: The Discovery of Elesclomol.”. Bioorganic & Medicinal Chemistry Letters 23 (18): 5070-6.

The synthesis of neoglycophospholipid conjugates via reductive amination of omega-oxoalkylglycosides and phosphatidylethanolamines.

Publication: Journal Article

Sun, L, and E L Chaikof. 1998. “The Synthesis of Neoglycophospholipid Conjugates via Reductive Amination of Omega-Oxoalkylglycosides and Phosphatidylethanolamines.”. Carbohydrate Research 307 (1-2): 77-81.

Neoglycophospholipids with alkyl spacers: synthesis via an improved reductive amination and monolayer properties.

Publication: Journal Article

Sun, L, and E L Chaikof. 1997. “Neoglycophospholipids With Alkyl Spacers: Synthesis via an Improved Reductive Amination and Monolayer Properties.”. Bioconjugate Chemistry 8 (4): 567-71.

In silico discovery and therapeutic potential of IDO1 and TDO2 inhibitors.

Publication: Journal Article

Jernigan, Finith E, and Lijun Sun. 2017. “In Silico Discovery and Therapeutic Potential of IDO1 and TDO2 Inhibitors.”. Future Medicinal Chemistry 9 (12): 1309-11.

Dr. Anh Tuan Pham

he/him

Person: Instructor

Anh-Tuan obtained his PhD in Chemistry at University of Geneva, Switzerland under the supervision of prof. Stefan Matile. His PhD research focused on designing supramolecular systems for organocatalysis based on peptide secondary structures. He also involved in the development of novel antivirals...