Volney L. Sheen Lab

Welcome to the Sheen Lab 

Join us in illuminating the biology of neurodegenerative diseases and epilepsy, transforming lives through discovery

Our Research

Volney L. Sheen, MD, PhD

 

 

 Our mission is to drive groundbreaking research that enhances the well-being of individuals living with neurodevelopmental and neurodegenerative diseases. Through innovation and collaboration, we strive to deepen our understanding and develop transformative treatment strategies. We welcomed dedicated and creative scientists to join us in this pursuit—working together to shape the future of neuroscience and make a meaningful impact on patients' lives.

Meet our team

 

Neuroscience Research

Our laboratory has three central areas of investigation:

  1. Generation and characterization of ventricular zone-derived human neural stem cells from developmental disorders of the central nervous system.
  2. Study of inherited disorders of cortical development, resulting from disruption of developmental processes along the ventricular zone.
  3. Study of different pathways involved in Alzheimer's disease and other neurodegenerative diseases.

 

Finding answers for neurological mysteries

Alzheimer's disease signaling pathways as targets for effective pharmacotherapy
Down Syndrome
Periventricular Heterotopia