The Biomarker & Metabolism Core provides access to Agilent Seahorse XFe analyzer, which measures and reports the oxygen consumption rate (OCR), proton efflux rate (PER) or extracellular acidification rate (ECAR), as well as ATP production rates of live cells in a 96-well format. OCR, PER, and ATP production rates are critical measurements of energy metabolism and vital indicators of mitochondrial health, toxicity, glycolysis, and overall cellular (dys)function. Together, these measurements provide a systems-level view of cellular metabolic function in cultured cells and ex vivo samples. For questions, please contact Dr. Xiaowen Liu at: xliu4@bidmc.harvard.edu.