Synthesis and terminal functionalization of a polymerizable phosphatidylethanolamine.

Sun, X L, H Liu, J M Orban, L Sun, and E L Chaikof. 2001. “Synthesis and Terminal Functionalization of a Polymerizable Phosphatidylethanolamine.”. Bioconjugate Chemistry 12 (5): 673-7.

Abstract

We report the design and synthesis of bifunctional phospholipid conjugates, which contain a polymerizable acrylate group and a terminal linker, such as biotin or N-(epsilon-maleimidocaproyl (EMC), to facilitate bioconjugation reactions. The lipid conjugate can be used to generate a multifunctional substrate-supported phospholipid film that is further stabilized via in-situ photocopolymerization.

Last updated on 10/11/2024
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