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The Lawler lab has studied the structure and function of the members of the TSP gene family for more than 50 years. We have focused on the role of TSP-1 in the tumor microenvironment. This research has informed the development of a new cancer therapeutic that is currently being evaluated in murine...

C57Bl/6J male mice were monitored in the Promethion indirect calorimeter, and data were analyzed in CalR to compare energy expenditure between T3-treated and vehicle groups (Hochbaum et al., Cell, 2024).

Mice expressing DREADDs and non-DREADD controls were monitored in the Promethion indirect calorimeter, with CNO administered at hour 4 and data plotted in CalR.

C57Bl/6J female mice were monitored for body temperature and metabolic rate during the dark photoperiod without food, with the blue trace representing a fed mouse and the red trace a fasted mouse exhibiting torpor (Hrvatin et al., Nature 2020). ​

Wheel-running activity was continuously recorded over several days, showing hourly running patterns and cumulative wheel counts across alternating light and dark cycles. ​

There are two main areas of research in the Banks lab: 1)Type 2 Diabetes Therapeutics 2) Regulation of Energy Balance. Scroll over the dropdown above to read more about these areas of research.

Functional MRI Processing for Mouse Micturition Studies Functional MRI (fMRI) studies in rodents is somewhat uncommon as it requires some cognitive or physiological stimulus that causes measurable changes in brain activity. This project however, lends itself well to fMRI studies as voiding induced...