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BIDMC Clinical Trials Database Title PI Gender Age Range Recruit Healthy Volunteers? Contact MRI Evaluation of Aging Related Changes to the Brain David Alsop, PhD All 18 years to 100 years Yes For info regarding 2017P000491, contact David Alsop at 617-667-0275 or dalsop@bidmc.harvard.edu Outcome...

Male C57Bl/6J mice (10–14 weeks, JAX) were monitored in the Promethion indirect calorimeter at 30°C, 23°C, and 4°C, tracking body weight and energy expenditure, with data analyzed in CalR. ​

Mice expressing DREADDs and non-DREADD controls were monitored in the Promethion indirect calorimeter, with CNO administered at hour 4 and data plotted in CalR.

C57Bl/6J male mice were monitored in the Promethion indirect calorimeter, and data were analyzed in CalR to compare energy expenditure between T3-treated and vehicle groups (Hochbaum et al., Cell, 2024).

Analysis of diet-induced obesity experiments in male C57Bl/6J mice on a low-fat diet (LFD) or high-fat diet (HFD), demonstrating differences in body weight, energy intake, expenditure, and balance (Banks et al., Nature Metabolism, 2025). ​

Wheel-running activity was continuously recorded over several days, showing hourly running patterns and cumulative wheel counts across alternating light and dark cycles. ​

Physical activity was monitored by infrared beam breaks in the Promethion indirect calorimeter for one hour in either a mouse with ad libitum access to food or shortly after food removal. (Rubio et al., Mol Metabolism, 2023)

Below is a breakdown of research student and postdoctoral research fellow positions. Hiring managers should select the title that best matches your new hire when completing the new hire or extension intake form on REDCap. Research Student Positions: Postdoctoral Fellow Positions:

Our facility offers comprehensive, end-to-end support for protein production, structural biology, and biophysical characterization—whether your goal is basic research, drug discovery, or translational development. Molecular Biology & Cloning Custom cloning of your gene of interest into a wide range...