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4] Facts About: Glycosylation of Cholesterol

By: Richard D. Cummings Cholesterol can be glycosylated, and indeed glucosylated cholesterol is common (1). In animal cells, it is a β-D-glucopyranoside derivative of cholesterol (GlcChol), which is generated through a ‘transglycosylation’ pathway in the lysosomes, by the enzymes glucocerebrosidase...

Methods

Functional MRI Processing for Mouse Micturition Studies Functional MRI (fMRI) studies in rodents is somewhat uncommon as it requires some cognitive or physiological stimulus that causes measurable changes in brain activity. This project however, lends itself well to fMRI studies as voiding induced...

Dr. Jordan Strom

Dr. Jordan Strom is Associate Professor of Medicine at Harvard Medical School, Director of the Echocardiography Laboratory, Director of Echocardiographic Research at Beth Israel Deaconess Medical Center in Boston, Massachusetts, and Section Head for Cardiovascular Imaging Research at the Richard A...

Aging Research

Aging research is critically important for medicine and public health with the anticipated surge in the older population with the aging of the Baby Boom generation. Investigators within the Division are conducting studies designed to improve our understanding and management of acute and chronic...