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Results - Obtained Under Urethane Anesthesia Regions that show activation during CMG peak include the Pontine Micturition Center (PMC), the Periaqueductal Gray (PAG) and the Hypothalamus. The PMC is a small center in the hindbrain that we now know activates bladder contractions, whereas the PAG...

In our laboratory, we study mechanisms of innate immune activation in liver diseases and its role on modulation of liver parenchymal cells including hepatocytes and stellate cells. We employ a broad range of preclinical murine liver injury models of alcohol-associated hepatitis, metabolic...

Biomarkers in Liver Disease We are exploring novel therapies and biomarker discoveries in AH. Direct effects of alcohol on hepatocytes, increased intestinal permeability and activation of innate immune system (Kupffer cells) by gut-derived LPS are major factors in AH leading to over-activation of...

Personalized Computational Modeling to Support Effective Use of Back Support Exosuits to Prevent Back Injuries Musculoskeletal back injuries are a major burden on society. However, exosuits may be able to help protect against some lifting injuries. Therefore, the aim of this study is to evaluate how...

Trunk neuromuscular control – the ability to accurately and precisely move the spine – may be an important factor underlying balance and physical function. While this control is impaired in patients with back pain, it has not been studied in relation to balance or physical function in older people...

Harvard-Affiliated Radiology Training at BIDMC The Department of Radiology at Beth Israel Deaconess Medical Center offers rigorous, highly specialized, and rewarding residencies, fellowships, and additional medical education opportunities. We are passionate about training and instilling confidence...