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Guilherme is attending Strasbourg Summer School In Chemoinformatics – 2024

News: June 18, 2024

Guilherme is attending Strasbourg Summer School In Chemoinformatics – 2024 The 9th Strasbourg Summer School in Chemoinformatics (CS3-2024) is to be held in Strasbourg, France, from June 24th to June 28th, 2024. If you attend the Summer School, don't hesitate to have a chat with Guilherme about our...

Total Synthesis of a PSGL-1 Glycopeptide Analogue for Targeted Inhibition of P-Selectin.

Publication: Journal Article

Dhakal, Bibek, Appi Mandhapati, Pradheep Eradi, Simon Park, Kirby Fibben, Kaicheng Li, Ashley DeYong, et al. 2024. “Total Synthesis of a PSGL-1 Glycopeptide Analogue for Targeted Inhibition of P-Selectin.”. Journal of the American Chemical Society 146 (25): 17414-27.

Indolyl-chalcone derivatives trigger apoptosis in cisplatin-resistant mesothelioma cells through aberrant tubulin polymerization and deregulation of microtubule-associated proteins.

Publication: Journal Article

Steinlein, Sophia, Frank Essmann, Amanda Franceschini Ghilardi, Heike Horn, Julia Schüler, Angelika Hausser, Lijun Sun, German Ott, and Claudia Kalla. 2023. “Indolyl-Chalcone Derivatives Trigger Apoptosis in Cisplatin-Resistant Mesothelioma Cells through Aberrant Tubulin Polymerization and Deregulation of Microtubule-Associated Proteins.”. Frontiers in Oncology 13: 1190988.

A PSGL-1 glycomimetic reduces thrombus burden without affecting hemostasis.

Publication: Journal Article

Wong, Daniel J, Diane D Park, Simon S Park, Carolyn A Haller, Jiaxuan Chen, Erbin Dai, Liying Liu, et al. 2021. “A PSGL-1 Glycomimetic Reduces Thrombus Burden Without Affecting Hemostasis.”. Blood 138 (13): 1182-93.

Discovery of furan carboxylate derivatives as novel inhibitors of ATP-citrate lyase via virtual high-throughput screening.

Publication: Journal Article

Jernigan, Finith E, Jun-Ichi Hanai, Vikas P Sukhatme, and Lijun Sun. 2017. “Discovery of Furan Carboxylate Derivatives As Novel Inhibitors of ATP-Citrate Lyase via Virtual High-Throughput Screening.”. Bioorganic & Medicinal Chemistry Letters 27 (4): 929-35.

A Cell-Based High-Throughput Screening for Inducers of Myeloid Differentiation.

Publication: Journal Article

Radomska, Hanna S, Finith Jernigan, Sohei Nakayama, Susan E Jorge, Lijun Sun, Daniel G Tenen, and Susumu S Kobayashi. 2015. “A Cell-Based High-Throughput Screening for Inducers of Myeloid Differentiation.”. Journal of Biomolecular Screening 20 (9): 1150-9.

Syntheses and antitumor activities of N'1,N'3-dialkyl-N'1,N'3-di-(alkylcarbonothioyl) malonohydrazide: the discovery of elesclomol.

Publication: Journal Article

Chen, Shoujun, Lijun Sun, Keizo Koya, Noriaki Tatsuta, Zhiqiang Xia, Timothy Korbut, Zhenjian Du, et al. 2013. “Syntheses and Antitumor Activities of N’1,N’3-Dialkyl-N’1,N’3-Di-(alkylcarbonothioyl) Malonohydrazide: The Discovery of Elesclomol.”. Bioorganic & Medicinal Chemistry Letters 23 (18): 5070-6.

The synthesis of neoglycophospholipid conjugates via reductive amination of omega-oxoalkylglycosides and phosphatidylethanolamines.

Publication: Journal Article

Sun, L, and E L Chaikof. 1998. “The Synthesis of Neoglycophospholipid Conjugates via Reductive Amination of Omega-Oxoalkylglycosides and Phosphatidylethanolamines.”. Carbohydrate Research 307 (1-2): 77-81.

Neoglycophospholipids with alkyl spacers: synthesis via an improved reductive amination and monolayer properties.

Publication: Journal Article

Sun, L, and E L Chaikof. 1997. “Neoglycophospholipids With Alkyl Spacers: Synthesis via an Improved Reductive Amination and Monolayer Properties.”. Bioconjugate Chemistry 8 (4): 567-71.

In silico discovery and therapeutic potential of IDO1 and TDO2 inhibitors.

Publication: Journal Article

Jernigan, Finith E, and Lijun Sun. 2017. “In Silico Discovery and Therapeutic Potential of IDO1 and TDO2 Inhibitors.”. Future Medicinal Chemistry 9 (12): 1309-11.