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Danger signals and pathways of macrophage activation in NASH Inflammatory cell activation drives diverse cellular programming in steatohepatitis. Our studies revealed that activation of the multiprotein complex, inflammasome, contributes to non-alcoholic steatohepatitis (NASH) involving the NLRP3...

Experiments proposed in this supplement will explore novel signaling molecules in alcohol-induced neuroinflammation and interactions between alcohol use and key pathways in the biology of neuroinflammation and AD dementia. Our studies will reveal new potential therapeutic targets in the dual insult...

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The Statistical Support Core offers free office hours for the BIDMC community, where members can book a meeting with a Biostatistician to discuss statistical questions related to their research projects. Time: Every other Tuesday, 12:00 – 1:00 pm EST Platform: Zoom Reserve Your Time Please use this...

Payment Models Direct grants support (a percentage of a statistician’s effort) assigned to a grant plus Core fee Hourly charges PhD Federal $110/hour Industry $132/hour

Within the Division, Dr. Gloria Yeh leads a program of mind-body and integrative medicine research. Integrative medicine is a healing-oriented approach that considers the entire person- encompassing cross-systems physiology, bio-psycho-social, and lifestyle aspects of health- and incorporates the...

3000 tank Aquatic Habitats recirculating water system (1, 5, 10L tanks), including nursery area 2 stand-alone isolation/quarantine units 2 Labconco steam scrubber dishwashers 2 Miele dishwashers 4 Harvard Apparatus microinjectors 4 Nikon stereomicroscopes 1 Variable temperature incubator 4 Vibration...

Housing and general care of Zebrafish (feeding, health monitoring, system maintenance) Propagation of wild-type Zebrafish stocks for embryo production Training in Zebrafish handling and husbandry Assistance with Zebrafish protocol planning and preparation Shipping and receiving live Zebrafish