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Sarah Juvera

Person: Undergraduate Student

Sarah joined the lab in 2023 as a freshman at Northeastern University studying Behavioral Neuroscience. She is helping with projects surrounding the cognitive and behavioral effects of traumatic brain Injuries and ischemic stroke.

Society for Neuroscience 2024

News: September 27, 2024

Join Dr. Amelia Douglass as she presents her recent collaborative work with Dr. Machado on, "A hypothalamic circuit for fasting-induced torpor" at the Society for Neuroscience meeting in Chicago from October 5-9. Neuroscience 2024

A Glutamatergic Hypothalamomedullary Circuit Mediates Thermogenesis, but Not Heat Conservation, during Stress-Induced Hyperthermia

Publication: Journal Article

Machado, Natalia L.S., Stephen B G Abbott, Jon M and Resch, Lin Zhu, Elda Arrigoni, Bradford B. Lowell, Marco A. P. Fontes, and Clifford B. Saper. 2018. “A Glutamatergic Hypothalamomedullary Circuit Mediates Thermogenesis, But Not Heat Conservation, During Stress-Induced Hyperthermia”. Current Biology 28 (14): 2291-2301.

Fever

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Stress-Induced Hyperthermia

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2024 BIDMC Research Retreat

News: August 30, 2024

Dr. Luis Costa will be presenting his recent work on "A Neuroprotective state of suspended animation" at the 2024 Beth Israel Deaconess Medical Center Research Retreat on the morning of Thursday, September 5th. Additionally, at the same time, Nicole Lynch will be presenting the collaborative work of...

David Melville

Person: Research Assistant (2023-2024)

David joined the Machado Lab in March of 2023 after graduating from Harvard College with a Bachelor of Arts degree in Neuroscience at the end of 2022. Previously, David completed his senior thesis in the Stevens Lab at Boston Children’s Hospital, and also spent a summer helping with immunology and...

Andy Chen

Person: Undergraduate Student (Summer 2024)

Perla Alpizar Chacon

Person: Undergraduate Student

Perla joined the lab in August of 2024 to conduct her undergraduate thesis. She is currently pursuing a bachelor in Bioscience's in Tecnologico de Monterrey at Mexico city. Perla has previous research experience working with the Metabolic Disorders Research Unit at the National Institute of Medical...

Preoptic EP3R neurons constitute a two-way switch for fever and torpor

Publication: Journal Article

Machado, Natalia L.S., Nicole Lynch, Luis H. A. Costa, David Melville, Hakan Kucukdereli, Satvinder Kaur, Alexander S. Banks, et al. 2025. “Preoptic EP3R Neurons Constitute a Two-Way Switch for Fever and Torpor”. Nature.