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Team

The PRM Core is comprised of a team of research technicians, software engineers, database developers and support staff at the doctoral level working under the direction of the PRM Core Directors. PRM staff provide biomedical data analysis, scientific systems administration, software and algorithm...

Delivery Unit

We can perform delivery of RNA via nanoparticle packaging both in vitro and in vivo using NanoAssemblr technology from Precision NanoSystems.​ ​Using an off-the-shelf lipid (Genvoy-ILM), the core can deliver siRNAs, miRNAs, mRNA, and more. Additionally, clients can use their own lipids and test...

Detection Unit

The Detection Unit of the Precision RNA Medicine Core offers two main services: MicroRNA Screening (targeted panels) Our unit offers full service microRNA screening of bio specimens using Mirxes ID3EAL™ assays. This highly sensitive qPCR-based technology can simultaneously screen for up to 376...

Frank Slack, PhD

Meet Dr. Frank Slack, our Co-Director of the Precision RNA Medicine Core at BIDMC. He is also the Shields Warren Mallinckrodt Professor in the Department of Pathology, and the director of the HMS Initiative for RNA Medicine. Dr. Slack's academic journey began with a BSc from the University of Cape...

Bioinformatics Unit

We provide a broad range of analytical services and grant development support. We analyze high throughput sequencing data, including bulk and snRNA seq, coding and noncoding RNA and genomics. We also provide consultation and support for coding and non-coding RNA research. The core is Directed by Dr...