Detection Unit

detection

The Detection Unit of the Precision RNA Medicine Core offers two main services:

  • MicroRNA Screening (targeted panels)

    Our unit offers full service microRNA screening of bio specimens using Mirxes ID3EAL™ assays. This highly sensitive qPCR-based technology can simultaneously screen for up to 376 microRNAs. We offer the following panels:

    • ID3EAL™ PanoramiR Panel targets 376 miRNAs involved in signaling pathways or disease mechanism
    • ID3EAL™ Cancer Panel targets 352 miRNAs commonly studied in cancer
  • Next Generation Sequecing (via third party vendor)

    Our unit offers sequencing services at special discounted rates for BIDMC researchers:

    • Whole Genome Sequencing (30x/50x/70x/100x; PE150)
    • Whole Genome Methylation Sequencing (30x/100x/200x; PE150)
    • Whole Exome Sequencing (50x/100x/250x; PE100)
    • RNA-Seq (40M/60M/100M; PE150)

Rates

Service List & Pricing (Updated April 02, 2024)

 

BIDMC Price

External Academic

External Corporate

microRNA Screening Assays*

 

 

 

  1. Mirxes Cancer Panel (each)

$380.00

$570.00

$760.00

  1. Mirxes PanoramiR Panel (each)

$429.00

$643.50

$858.00

  1. Maxwell® RNA extraction (each sample)

$24.00

$36.00

$48.00

  1. RNA extraction (Labor; per 16 samples)

$118.00

$177.00

$236.00

  1. cDNA and augmentation (Labor; per 16 samples)

$248.00

$372.00

$496.00

  1. Mirxes Panel qPCR assay run (Labor; per panel)

$79.00

$118.50

$158.00

Next Generation Sequencing (NGS)#

 

 

 

  1. Whole Genome Sequencing (WGS)
     30x PE150 (90 Gb; T10; each)

$413.00

NA

NA

  1. Whole Genome Methylation Sequencing (WGMS)
     30x PE 150 (90 Gb; T10; each)

$767.00

NA

NA

  1. Whole Exome Sequencing (WES)
    50x PE100 (5 Gb; Twist 2.0; each)

$203.00

NA

NA

  1. RNA Sequencing
    40M PE150 (T7; each)

$196.00

NA

NA

* Please see next portion for an example how costs are calculated.

# Via an external third-party vendor; shipping to be added on. Bioinformatics not included.

Example scenario of how microRNA screening assays are calculated

  • Client would like to screen 18 mouse liver samples using the PanoramiR Panel:

Procedure

Cost

Quantity

Total

  1. RNA extraction reagents (each)

$24

18

$432

  1. RNA extraction labor (per 16 samples)

$118

2

$236

  1. cDNA & augmentation labor (per 16 samples)

$248

2

$496

  1. PanoramiR panel (reagent; each)

$429

18

$7722

  1. Panel assay labor (each)

$79

18

$1422

Total cost

$10,308

  • Each sample costs $573 to quantify 376 microRNAs. The cost to measure 1 microRNA is $1.52.