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Indirect Calorimetry Systems

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Sable Systems Promethion indirect calorimeter (32 cages) Food intake Water intake In-cage body mass measurement Physical activity (infrared beam breaks) Energy expenditure Oxygen consumption (VO2) Carbon dioxide production (VCO2) Respiratory exchange ratio – an indicator of carbohydrate or fat...

Diet-induced obesity

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Analysis of diet-induced obesity experiments in male C57Bl/6J mice on a low-fat diet (LFD) or high-fat diet (HFD), demonstrating differences in body weight, energy intake, expenditure, and balance (Banks et al., Nature Metabolism, 2025). ​

Optogenetic stimulation of food intake

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Optogenetic stimulation of Agrp neurons in ChR2-expressing mice was performed in the Promethion calorimeter, with food intake, metabolic rate, body temperature, and activity measured during the stimulation period.

[Sample] Transhumanism and Posthumanism: Future Visions of Humanity.

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The course examines the philosophical and technological developments around Transhumanism and Posthumanism. Students will engage with futurist theories, bioethics, and the potential impacts of advancements such as genetic engineering, neuroenhancement, and artificial intelligence. Through...

Trans-ethnic meta-regression of genome-wide association studies accounting for ancestry increases power for discovery and improves fine-mapping resolution.

Publication: Journal Article
Mägi, Reedik, Momoko Horikoshi, Tamar Sofer, Anubha Mahajan, Hidetoshi Kitajima, Nora Franceschini, Mark I McCarthy, T2D-GENES Consortium COGENT-Kidney Consortium, and Andrew P Morris. 2017. “Trans-Ethnic Meta-Regression of Genome-Wide Association Studies Accounting for Ancestry Increases Power for Discovery and Improves Fine-Mapping Resolution.”. Human Molecular Genetics 26 (18): 3639-50.

Genome-Wide Association Study of Heavy Smoking and Daily/Nondaily Smoking in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

Publication: Journal Article
Saccone, Nancy L, Leslie S Emery, Tamar Sofer, Stephanie M Gogarten, Diane M Becker, Erwin P Bottinger, Li-Shiun Chen, et al. 2018. “Genome-Wide Association Study of Heavy Smoking and Daily/Nondaily Smoking in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).”. Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco 20 (4): 448-57.