Research

This lab focuses on a broad range of neuromuscular disorders, including ALS, muscular dystrophy, spinal muscular atrophy, polyneuropathies, inflammatory myopathies, and radiculopathy.

Our lab also displays a great interest on muscle disuse, such as the one experience during spaceflight. We focus more particularly in developing a partial gravity analog model to study space-travel induced musculoskeletal deconditioning and helping develop new countermeasures. Many of our studies are NASA funded. 

Much of our research involves the application of electrophysiological measures, imaging modalities, and innovative bioengineering approaches to diagnose and treat these disorders. These techniques include electrical impedance myography, quantitative ultrasound, magnetic resonance imaging, and nerve and muscle excitability techniques. We are also interested in studying mechanisms of disease pathogenesis and testing new therapeutic agents that can improve function and health. Some of our longer term goals include developing novel, powerful biomarkers to assist with disease diagnosis, the assessment of progression, and the effect of therapy.