The VanderHorst lab studies
- how distinct brainstem neuronal systems dynamically modulate different fundamental functions ranging from walking gait, muscle tone, respiration, to arousal
- how age-related and neurodegenerative changes in these circuits that occur in the setting of Parkinson’s Disease and Alzheimer’s Disease correlate with treatment resistant symptoms such as walking and balance problems, dystonias and sleep disordered breathing.
The overall goal is to develop approaches to promote function and wellbeing.