Publications

Celada M, Zaarour N, Cheung J, Gross C, Lim A, Buchman AS, Saberi P, Varma G, VanderHorst V. Standardization of postmortem human brainstem along the rostrocaudal axis to accommodate for inter-specimen structural heterogeneity. Sci Rep. 2025 Oct 15;15(1):36064. doi: 10.1038/s41598-025-20016-7.PMID: 41093927

Oveisgharan S, Collin A, Yang J, Leurgans SE, VanderHorst V, Bennett DA, Cohen-Adad J, Delbono O, Buchman AS. Morphometric characteristics of tibial nerve and their relationship with age. Brain Commun. 2025 Jul 7;7(4):fcaf267. doi: 10.1093/braincomms/fcaf267. eCollection 2025.

Eitan E. Asher, Eran Gazit, Nasim Montazeri, Elisa Mejía-Mejía, Rachel Godfrey, David A. Bennett, Veronique G. VanderHorst, Aron S. Buchman, Andrew S. P. Lim, Jeffrey M. Hausdorff. Combining 24-Hour Continuous Monitoring of Time-Locked Heart Rate, Physical Activity and Gait in Older Adults: Preliminary Findings. Sensors 2025, 25(6), 1945; https://doi.org/10.3390/s25061945

Buchman AS, Yu L, Oveisgharan S, Zammit AR, Wang T, Shulman JM, VanderHorst V, Nag S, Bennett DA. Parkinson's Disease and Other Alzheimer's Disease and Related Dementia Pathologies and the Progression of Parkinsonism in Older Adults. J Alzheimers Dis. 2024;100(s1):S197-S209. doi: 10.3233/JAD-240593. PMID: 39121125.

Activation of Medullary Serotonergic Cell Subtypes Differentially Modulates Breathing, Upper Airway Tone, and Arousal During Sleep as Relevant for Sleep-Disordered Breathing. Parastoo Saberi, Kathryn M. Lehigh, Anh Khoa Tran, Susan M. Dymecki, Veronique VanderHorst. Annals of Neurology Vol 96 (suppl 32) 2024, page S292. 

Audrey Worley, Alana Kirby, Sophie Luks, Tamara Samardzic, Brian Ellison, Lauren Broom, Alban Latremoliere, Veronique G VanderHorst. Contrasting walking styles map to discrete neural substrates in the mouse brainstem BioRxiv 537568; doi: https://doi.org/10.1101/2023.04.19.537568 PREPRINT

Buchman AS, Leurgans SE, Kim N, Agrawal S, Oveisgharan S, Zammit AR, VanderHorst V, Nag S, Bennett DA Alzheimer's Disease Pathology Outside of the Cerebrum Is Related to a Higher Odds of Dementia..J Alzheimers Dis. 2023 Oct 9. doi: 10.3233/JAD-230223. PMID: 37840485.

Buchman AS, Capuano AW, VanderHorst V, Wilson RS, Oveisgharan S, Schneider JA, Bennett DA. Brain β-Amyloid Links the Association of Change in Body Mass Index With Cognitive Decline in Community-Dwelling Older Adults. J Gerontol A Biol Sci Med Sci. 2023 Feb 24;78(2):277-285. doi: 10.1093/gerona/glab320.

Joshi K, Kirby A, Niu J, VanderHorst VG. Stereotaxic surgical approach to microinject the caudal brainstem and upper cervical cord via the cisterna magna in mice. J Vis Exp (2022) 179. Doi:10.3791/63344.

Lauren Broom, Jessica Stephen, Varun Nayar, Veronique G VanderHorst. Shifts in gait signatures mark the end of lifespan in mice, with sex differences in timing. Front. Aging Neurosci., 02 August 2021  doi:10.3389/fnagi.2021.716993. Epub August 2, 2021.

Manor B, Dagan M, Herman T, Gouskova NA, Vanderhorst VG, Giladi N, Travison TG, Pascual-Leone A, Lipsitz LA, Hausdorff JM. Multi-target transcranial electrical stimulation for freezing of gait: a randomized controlled trial. Movement Disorders (2021) 36(11) 2693-2698.doi:10.002/mds.28759.

Nag S, Yu L, VanderHorst VG, Schneider JA, Bennett DA, Buchman AS, Wilson RS. Neocortical Lewy bodies are associated with impaired odor identification in community-dwelling elders without clinical PD. J. Neurol. (2019) Sep 18. Doi: 10.1007/s00415-019-09540-5.

Anne M.J. Verstegen, Nataliya Klymko, Lin Zhu, John C. Mathai, Reina Kobayashi, Anne Venner, Rachel A. Ross, Veronique G. VanderHorst, Elda Arrigoni, Joel C. Geerling, and Mark L. Zeidel. Non-Crh glutamatergic neurons in Barrington’s nucleus control micturition via glutamatergic afferents from the midbrain and hypothalamus. Current Biology (2019) 9;29(17):2775-2789.

Broom L, Worley A, Gao F, Hernandez LD, Ashton CE, Shih LC, VanderHorst VG. Translational methods to detect asymmetries in temporal and spatial walking metrics in parkinsonian mouse models and human subjects with Parkinson’s disease. Sci Rep, (2019), 9:2437. https://doi.org/10.1038/s41598-019-38623-6.

Buchman AS, Leurgans SE, VanderHorst VGJM, Nag S, Schneider JA, Bennett DA. Spinal motor neurons and motor function in older adults. J Neurol. (2019) 266(1):174-182. PMID: 30446967.

Buchman AS, Nag S, Leurgans SE, Miller J, VanderHorst VGJM, Bennett DA, Schneider JA. Spinal Lewy body pathology in older adults without an antemortem diagnosis of Parkinson's disease. Brain Pathol. (2018). 28(4):560-568. PMID: 28960595.

Buchman AS, Leurgans SE, Nag S, VanderHorst VGJM, Kapasi A, Schneider JA, Bennett DA.  Spinal Arteriolosclerosis Is Common in Older Adults and Associated With Parkinsonism. Stroke. (2017);48(10):2792-2798. doi: 10.1161/STROKEAHA.117.017643.

Broom L, Ellison BA, Worley A, Wagenaar L, Sörberg E, Ashton C, Bennett DA, Buchman AS, Saper CB, Shih LC, Hausdorff JM, VanderHorst VG. A translational approach to capture gait signatures of neurological disorders in mice and humans. Sci Rep. (2017);7(1):3225. doi: 10.1038/s41598-017-03336-1.

Gross C, Ellison B, Buchman AS, Terasawa E, VanderHorst VG. A Novel Approach for Assigning Levels to Monkey and Human Lumbosacral Spinal Cord Based on Ventral Horn Morphology. PLoS One. (2017); 12(5): e0177243.

Verstegen AM, Vanderhorst V, Gray PA, Zeidel ML, Geerling JC. Barrington's nucleus: Neuroanatomic landscape of the mouse "pontine micturition center". J Comp Neurol. (2017) 525(10):2287-2309.

Buchman NM, Leurgans SE, Shah RJ, VanderHorst V, Wilson RS, Bachner YG, Tanne D, Schneider JA, Bennett DA, Buchman AS. Urinary Incontinence, Incident Parkinsonism, and Parkinson's Disease Pathology in Older Adults. J Gerontol A Biol Sci Med Sci. (2016). pii: glw235.

Graebner AK, Tarsy D, Shih LC, Vanderhorst V, Kulkarni O, Kaplan S, Simon DK. Clinical Impact of 123I-Ioflupane SPECT (DaTscan) in a Movement Disorder Center. Neurodegener Dis. (2017);17(1):38-43.

Buchman NM, Leurgans SE, Shah RJ, VanderHorst V, Wilson RS, Bachner YG, Tanne D, Schneider JA, Bennett DA, Buchman AS. Urinary Incontinence, Incident Parkinsonism, and Parkinson's Disease Pathology in Older Adults. J Gerontol A Biol Sci Med Sci. (2016) Dec 7.

Buchman AS, Yu L, Wilson RS, Dawe RJ, VanderHorst V, Schneider JA, Bennett DA. Post-mortem brain pathology is related to declining respiratory function in community-dwelling older adults. Front Aging Neurosci. (2015);7:197.

VanderHorst VG, Samardzic T, Saper CB, Anderson MP, Nag S, Schneider JA, Bennett DA, Buchman AS. α -synuclein pathology accumulates in sacral spinal visceral sensory pathways. Ann Neurol. (2015);78(1):142-9.

Yokota S, Kaur S, VanderHorst VG, Saper CB, Chamberlin NL. Respiratory-related Outputs of Glutamatergic, Hypercapnia-Responsive Parabrachial Neurons in Mice. J Comp Neurol. (2014).

Buchman, A. S. Leurgans, S. E. Weiss, A. Vanderhorst, V. Mirelman, A. Dawe, R. Barnes, L. L. Wilson, R. S. Hausdorff, J. M., Bennett, D. A. Associations between Quantitative Mobility Measures Derived from Components of Conventional Mobility Testing and Parkinsonian Gait in Older Adults. PLoS One. (2014); 9(1): e86262.

Shih LC, Vanderhorst V, Lozano AM, Hamani C, and Moro E. Improvement of Pisa syndrome with contralateral pedunculopontine stimulation. Movement Disorders (2013) 28 (4): 555-6.

Suidan GL, Duerschmied D, Dillon GM, Vanderhorst V, Hampton TG, Wong SL, Voorhees JR, Wagner DD. Lack of tryptophan hydroxylase-1 in mice results in gait abnormalities. PLoS One. (2013);8(3):e59032.

Buchman AS, Nag S, Shulman JM, Lim ASP, VanderHorst VG, Leurgans SE, Schneider JA, Bennett DA. Aminergic nuclei neuron density and Parkinsonism in older adults without Parkinson’s Disease. Movement Disorders. Movement Disorders. (2012) 27(13):1625-31.

Shih LC, Piel J, Warren A, Kraics L, Silver A, Vanderhorst V, Simon DK, Tarsy D. Singing in groups for Parkinson's disease (SING-PD): A pilot study of group singing therapy for PD-related voice/speech disorders. Parkinsonism Relat Disord (2012) 18: 548-552.

Spinal projections of the A5, A6 (locus coeruleus) and A7 noradrenergic cell groups in rats. Bruinstroop E, Cano G, Vanderhorst VG, Cavalcante JC, Wirth J, Sena-Esteves M, Saper CB. J Comp Neurol. J Comp Neurol. (2012) 520(9):1985-2001.

Shih LC, Vanderhorst V, Papavassiliou E, Tarsy D. Sustained Dyskinesias Following Elective Cessation and Reactivation of Chronic Subthalamic Nucleus Deep Brain Stimulation for a Surgical Procedure. Neuromodulation. Neuromodulation. (2011) 14(6):512-4.

Lungu C, Tarulli AW, Tarsy D, Mongiovi P, Vanderhorst VG, Rutkove SB. Quantifying muscle asymmetries in cervical dystonia with electrical impedance: a preliminary assessment. Clin Neurophysiol. (2011) 122(5):1027-31.

VanderHorst, V.G., E. Terasawa, and H.J. Ralston III. Estrogen receptor-alpha immunoreactive neurons in the brainstem and spinal cord of the female rhesus monkey: species-specific characteristics. Neuroscience. (2009) 158: 798-810.

VanderHorst, V.G., E. Papavassiliou, D. Tarsy, and L. Shih. Early brain abscess: A rare complication of deep brain stimulation. Movement Disorders (2009) 24(9):1395-7.

VanderHorst, V.G. and B. Ulfhake. The organization of the brainstem and spinal cord of the mouse: Relationships between monoaminergic, cholinergic, and spinal projection systems. J Chem Neuroanat. (2006) 31: 2-36. Featured on Cover.

VanderHorst, V.G., J-Å Gustafsson, and B. Ulfhake. Estrogen receptor-alpha and -beta immunoreactive neurons in the brainstem and spinal cord of male and female mice: relationships to monoaminergic, cholinergic, and spinal projection systems. J. Comp. Neurol. (2005) 488: 152-179.

VanderHorst, V.G The nucleus retroambiguus-spinal pathway in the mouse: localization, gender differences, and effects of estrogen treatment. J. Comp. Neurol. (2005) 488: 180-200.

VanderHorst, V.G., E. Terasawa, and H.J. Ralston III. Projections from estrogen receptor- immunoreactive neurons in the periaqueductal gray to the lateral medulla oblongata in the ovariectomized rhesus monkey. Neuroscience (2004) 125: 243-253.

VanderHorst, V.G., E. Terasawa, and H.J. Ralston III. Axonal sprouting of a brainstem-spinal pathway after estrogen administration in the adult female rhesus monkey. J. Comp. Neurol. (2002) 454: 82-103.

VanderHorst, V.G., E. Terasawa, and H.J. Ralston III. Estrogen receptor-alpha immunoreactive neurons in the ventrolateral periaqueductal gray receive monosynaptic input from the lumbosacral cord in the rhesus monkey. J. Comp. Neurol. (2002) 443:27-42.

Yakovenko S, Mushahwar V, VanderHorst V, Holstege G, Prochazka A. Spatiotemporal activation of lumbosacral motoneurons in the locomotor stepcycle. J. Neurophysiol. (2002) 87: 1542-1553. Featured on Cover.   

VanderHorst, V.G., E. Terasawa, and H.J. Ralston III. Monosynaptic projections from the nucleus retroambiguus region to laryngeal motoneurons in the rhesus monkey. Neurosci. (2001) 107: 117-125.

VanderHorst, V.G., E. Meijer, and G. Holstege. Estrogen receptor-alpha immunoreactivity in parasympathetic preganglionic neurons innervating the bladder in the adult ovariectomized female cat. Neurosci. Lett. (2001) 298:147-150.

VanderHorst, V.G., E. Terasawa, H.J. Ralston III, and G. Holstege. Monosynaptic projections from the lateral caudal periaqueductal gray to the nucleus retroambiguus in the rhesus monkey: implications for vocalization and reproductive behavior. J. Comp. Neurol. (2000) 424: 251-268.

VanderHorst, V.G., E. Terasawa, H.J. Ralston III, and G. Holstege. Monosynaptic projections from the nucleus retroambiguus to motoneurons supplying the abdominal wall, axial, hindlimb, and pelvic floor in the female rhesus monkey. J. Comp. Neurol. (2000) 424: 233-250.

VanderHorst, V.G., and G. Holstege. Sensory and motor components of reproductive behavior: pathways and plasticity. Behav. Brain Res. (1998) 92:157-167.

VanderHorst, V.G., F.C. Schasfoort, E. Meijer,  F.W. van Leeuwen, and G. Holstege. Estrogen receptor-alpha-immunoreactive neurons in the periaqueductal gray of the adult ovariectomized female cat. Neurosci. Lett. (1998) 240:13-16.

VanderHorst, V.G., H. deWeerd, and G. Holstege. Evidence for monosynaptic projections from the nucleus retroambiguus to hindlimb motoneurons in the cat. Neurosci. Lett. (1997) 224: 33-36.

Mouton L.J., V.G. VanderHorst, and G. Holstege. Large segmental differences in the spinal projections to the periaqueductal gray in the cat. Neurosci. Lett. (1997) 238:1-4.

Holstege, G., L. Kerstens, M C. Moes, and V.G. VanderHorst. Evidence for a periaqueductal gray - nucleus retroambiguus - spinal cord pathway in the rat. Neuroscience (1997) 80: 587-598.

VanderHorst, V.G., E. Meijer, F.C. Schasfoort, F.W. Van Leeuwen, and G. Holstege. Estrogen receptor-immunoreactive neurons in the lumbosacral cord projecting to the periaqueductal gray in the ovariectomized female cat. Neurosci. Lett. (1997) 236:25-28.

VanderHorst, V.G., and G. Holstege. Estrogen induces axonal outgrowth in the nucleus retroambiguus-lumbosacral motoneuronal pathway in the adult female cat. J. Neurosci. (1997) 17: 1122-1136.

VanderHorst, V.G., and G. Holstege. The organization of lumbosacral motoneuronal cell groups innervating hindlimb, pelvic floor and axial muscles in the cat. J. Comp. Neurol. (1997) 382: 46-76.

VanderHorst, V.G., and G. Holstege. Nucleus retroambiguus projections to lumbosacral motoneuronal cell groups in the male cat. J. Comp. Neurol. (1997) 382:77-88.

VanderHorst, V.G., and G. Holstege. A concept for the final common pathway of vocalization and lordosis behavior in the cat. Progr. Brain Res. (1996) 107: 327-341.

VanderHorst, V.G., L. J. Mouton, B. F. M. Blok, and G. Holstege. Distinct cell groups in the lumbosacral cord of the cat project to different areas in the periaqueductal gray. J. Comp. Neurol. (1996) 376: 361-385.

VanderHorst, V.G., and G. Holstege. Caudal medullary pathways to lumbosacral motoneuronal cell groups in the cat: evidence for direct projections possibly representing the final common pathway for lordosis. J. Comp. Neurol. (1995) 359:  457-475.