Participation

Who can participate?

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You may be able to participate if you:

Are a women ages 18 - 44 years old
Starting IVF - using your own eggs
Have 5 or fewer fertilized eggs the day after egg retrieval

You may not be able to participate if you:

Greater than 2 prior IVF cycles
Have more than 5 or no embryos on Day 1 after fertilization
Decide that embryos will be frozen and you will not undergo a fresh transfer
Known chromosomal abnormality
Decide to use non-ejaculated sperm
BMI is >40
Have a history of recurrent pregnancy loss (≥3 spontaneous abortions)
Have a presence of uterine factor infertility
There are delays in egg fertilization or problems with fertilization that may lead to sperm injected into an egg
You and your clinical team decide to transfer a number of embryos beyond what is recommended by the American Society of Reproductive Medicine
Pre-implantation genetic testing (PGT) preformed on all embryos

Note: Within the study IVF cycle, Pre-implantation Genetic Testing aneuploidy (PGT-A) may be performed on embryos remaining after initial fresh transfer

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After enrolling, what happens in the study?

If you are eligible and agree to participate we will:

Randomize you to receive an embryo(s) transfer on Day 3 or Day 5, which means you would be assigned to a group (at random) to transfer your embryo(s) on Day 3 OR Day 5

In this study, the only difference is the randomization of the day of transfer. All other procedures are a part of regular IVF care.

Our Study Team will work with your Clinical Team to let them know which group you have been randomized to
Follow you throughout your pregnancy
We will collect information (via email) about you, your pregnancy, and your IVF experience
Our study team may contact you, during participation, to ask clarifying questions regarding your medical history
You will be compensated and receive $1,000 for your time and effort if you agree and complete the study

Joining is completely up to you. If you choose not to participate or decide to stop at any time, it will not affect your care in any way.

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I want to participate! What's next?

Contact our PRECISE study site coordinator(s) from Boston IVF (Massachusetts Locations) or Brigham Women's Hospital (Main Campus Location) where we are actively recruiting patients.

Click to Download Study Information

Boston IVF Brochure

Brigham Women's Hospital Brochure

Are you recruiting at other hospitals/locations?

As of now we are only recruiting at OB/GYN departments at Boston IVF (Massachusetts locations) and Brigham Women's Hospital (Main Campus location).

If you are interested in the study but already have established care or are interested in establishing care at another hospital, please make sure to check back with us later.

We will continue to update our site with new information and new enrollment partners as our study progresses.

General information about our partner sites and affiliates may be found here: General Information